Evidence map›Paper›PMID 41472202›Full record

ArticleViruses2025

New Circulating Variants of SARS-CoV-2 in Asturias During the Period (2022-2024).

José María González-Alba, Zulema Pérez Martínez, Susana Rojo-Alba, Cristina Ochoa Varela, Juan Gómez de Oña, Mercedes Rodríguez Pérez, Santiago Melón García, Marta Elena Álvarez-Argüelles

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José María González-AlbaUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Zulema Pérez MartínezUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Susana Rojo-AlbaUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Cristina Ochoa VarelaUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Juan Gómez de OñaUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-3318-4649
Mercedes Rodríguez PérezUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Santiago Melón GarcíaUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0001-5770-7902
Marta Elena Álvarez-ArgüellesUnit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-0958-2620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of a virus to adapt is key to its survival, and this is achieved through mutation, which allows the virus to change and adapt to new environments. To capture the full extent of SARS-CoV-2 diversity in Asturias, samples obtained from nasopharyngeal swabs were characterised using whole-genome sequencing. Between 2020 and July 2024, a total of 4001 sequences were analysed and 5302 mutations were identified. An increase in the positivity rate was observed between 2022 and 2024 in children under 1 year of age. During this period, 55 new circulating variants belonging to 41 pangolin lineages were detected: 24 originated throughout the world and 31 in Asturias (10 detected only in the region, 8 in the rest of Spain, and 13 around the world). A total of 31 new non-synonymous mutations were fixed in the viral population 250 ± 46 (93-620) days after their appearance. During seasonal SARS-CoV-2 circulation, surveillance systems developed during the pandemic continue to detect new indigenous and imported variants without indicating an increase in severity.

Indexed as

COVID-19SARS-CoV-2AdolescentAdultChildChild, PreschoolFemaleGenome, ViralHumansInfantInfant, NewbornMaleMiddle AgedMutationNasopharynxPhylogenynew variantsphylogenetic analysisSARS-CoV-2surveillance

Identifiers

PMID41472202
PMCPMC12737691

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.