ReviewVeterinary sciences2025
Good Veterinary Practices for Managing the Colostral Period in Dairy Calves to Improve Their Immune Competence-A Systematic Review.
Review in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Early Postpartum Change in Lactoferrin in Bovine Colostrum During the First 12 h Postpartum and Its Relationship with On-Farm Quality Indicators.Veterinary sciences · 2026Article
- Early blood biochemical changes following colostrum intake in newborn Murrah buffalo calves: an observational study.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Passive transfer of immunoglobulin G (IgG) through colostrum is essential for early immune protection in dairy calves. This systematic review synthesizes the most relevant evidence on colostrum quality, feeding practices, storage methods, and post-feeding assessment. High-quality colostrum (≥50 g/L IgG and low bacterial contamination) can be reliably assessed using Brix refractometry (≥22%) or radial immunodiffusion. Early administration is critical: feeding within 1-2 h after birth maximizes IgG absorption. Providing 8.5-10% of body weight (≈3-4 L) at first feeding, followed by a second feeding within 8-12 h, significantly reduces failure of passive transfer. Pasteurization at 60 °C for 60 min and controlled freezing maintain immunological integrity while reducing microbial load. Monitoring passive immunity using serum total protein (5.0-5.5 g/dL) or serum Brix (8.1-8.5%) offers practical field diagnostics aligned with the IgG ≥ 10 g/L threshold. Integrated colostrum management protocols-combining quality evaluation, timely feeding, hygienic handling, and trained personnel-are essential to improve passive immunity, health, and overall performance of dairy calves.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.