Evidence map›Paper›PMID 41472143›Full record

ArticleVeterinary sciences2025

Effects of Dietary Alpha-Ketoglutarate Supplementation on Diarrhea Incidence and Nutrient Digestibility in Weaned Piglets Fed Low-Protein Diets.

Weiyan Sun, Ruyi Han, Kaikun Huang, Wenning Chen, Zhiwen Bian, Luca Marchetti, Hongbo Xi, Valentino Bontempo, Xianren Jiang

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weiyan SunKey Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0009-0007-7306-0572
Ruyi HanKey Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Kaikun HuangShenzhen Xintianhe Biotechnology Co., Ltd., Shenzhen 518000, China.
Wenning ChenDepartment of Veterinary Medicine and Animal Science (DIVAS), University of Milan, 26900 Lodi, Italy.
Zhiwen BianKey Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Luca MarchettiDepartment of Veterinary Medicine and Animal Science (DIVAS), University of Milan, 26900 Lodi, Italy.ORCID 0000-0001-7550-7859
Hongbo XiShenzhen Xintianhe Biotechnology Co., Ltd., Shenzhen 518000, China.
Valentino BontempoDepartment of Veterinary Medicine and Animal Science (DIVAS), University of Milan, 26900 Lodi, Italy.ORCID 0000-0002-6195-0179
Xianren JiangKey Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0002-8799-3572

Funding

Agricultural Science and Technology Innovation Program CAAS-ASTIP-2023-IFR-15National Natural Science Foundation of China 32260850
6 · The paper itself

Abstract

Alpha-ketoglutarate (AKG) supplementation has been explored as a nutritional strategy to mitigate the negative effects of protein restriction. This study aims to evaluate the effects of supplementing a low-protein diet with AKG on growth performance, diarrhea incidence, and fecal nutrient digestibility in weaned piglets. A total of 60 weaned piglets (initial body weight: 7.53 kg; age: 28 days old) were randomly distributed into three dietary treatments with five replicates per group, for a 42-day experimental period. The treatments consisted of a control diet (CT), a low-protein diet (LP), and a low-protein diet supplemented with 1000 g/t AKG (AKG). Fecal samples were collected on days 40-42 to determine the apparent digestibility of nutrients. The results showed that the feed conversion rate (FCR) in LP-group piglets were significantly higher than that of the CT group (

Indexed as

feed additivegrowthshort-chain keto acidweaning piglets

Identifiers

PMID41472143
PMCPMC12737471

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.