Evidence map›Paper›PMID 41472040›Full record

ArticleMicroorganisms2025

Operative Risk Factors and Microbiologic Profiles of Deep Infection Following Pilon Fracture Fixation.

Jackson M Cathey, Crystal Jing, Julia E Ralph, Kathleen Chang, Alexandra Krez, Joshua Helmkamp, Anna Bryniarski, Conor O'Neill, Samuel Adams, Albert T Anastasio

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jackson M CatheySchool of Medicine, Duke University Health System, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.ORCID 0009-0007-6230-5044
Crystal JingSchool of Medicine, Duke University Health System, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.ORCID 0009-0002-4237-1718
Julia E RalphSchool of Medicine, Duke University Health System, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.ORCID 0009-0001-7703-9400
Kathleen ChangSchool of Medicine, Duke University Health System, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.
Alexandra KrezDepartment of Orthopaedic Surgery, Duke University Health System, Duke University, 2301 Erwin Road, Durham, NC 27710, USA.
Joshua HelmkampDepartment of Orthopaedic Surgery, Duke University Health System, Duke University, 2301 Erwin Road, Durham, NC 27710, USA.
Anna BryniarskiDepartment of Orthopaedic Surgery, Duke University Health System, Duke University, 2301 Erwin Road, Durham, NC 27710, USA.
Conor O'NeillDepartment of Orthopaedic Surgery, Duke University Health System, Duke University, 2301 Erwin Road, Durham, NC 27710, USA.ORCID 0000-0003-4456-9445
Samuel AdamsDepartment of Orthopaedic Surgery, Duke University Health System, Duke University, 2301 Erwin Road, Durham, NC 27710, USA.ORCID 0000-0003-1020-1167
Albert T AnastasioDepartment of Orthopaedic Surgery, Duke University Health System, Duke University, 2301 Erwin Road, Durham, NC 27710, USA.ORCID 0000-0001-5817-3826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep tissue infection is a serious complication following operative fixation of pilon fractures, yet the influence of intraoperative factors and microbial characteristics remains underexplored. In this retrospective review of 123 patients treated with open reduction and internal fixation, we evaluated demographic, injury-related, operative, and microbiologic variables associated with deep infection. Patients who developed infection had longer operative times than those who did not. This modestly powered study found that operative duration was not independently associated with infection risk after adjustment for key covariates. Larger studies are needed to confirm this finding. Deep infection rates did not differ by surgical approach or time to fixation. Nine patients (7.3%) developed deep infection, with cultures demonstrating a heterogeneous microbial profile most commonly including

Indexed as

fixationfractureinfectionoperative timeORIFpilon

Identifiers

PMID41472040
PMCPMC12735856

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.