Evidence map›Paper›PMID 41471881›Full record

ArticleMicroorganisms2025

Isavuconazole for the Treatment of Invasive Fungal Disease in Hematology Patients: A Real-World Retrospective Study on Efficacy and Safety.

Pazilaiti Tuohuti, Yuhui Chen, Ailin Zhao, Jinrong Yang, He Li, Ting Niu

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pazilaiti TuohutiDepartment of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu 610041, China.
Yuhui ChenDepartment of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0005-6245-4619
Ailin ZhaoDepartment of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jinrong YangDepartment of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu 610041, China.
He LiDepartment of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu 610041, China.
Ting NiuDepartment of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-1580-1014

Funding

1.3.5 Project of High Altitude Medicine No. GYYX24003West China Hospital, Sichuan University, and National Natural Science Foundation of China No. 82370192, U24A20680
6 · The paper itself

Abstract

Invasive fungal disease (IFD) remains a life-threatening complication in patients with hematological diseases. Isavuconazole was approved by the FDA for primary treatment of invasive aspergillosis and mucormycosis. While clinical trials have demonstrated its efficacy, data on its use in hematology patients remain limited. This study aims to evaluate the real-world effectiveness and safety of isavuconazole in this population. We conducted a single-center, retrospective study of hematology patients who received isavuconazole for IFD between 1 June 2022, and 31 July 2024, at West China Hospital, Sichuan University. A total of 66 patients with proven (

Indexed as

hematology patientsinvasive fungal diseaseisavuconazoleprognosis

Identifiers

PMID41471881
PMCPMC12735052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.