Evidence map›Paper›PMID 41471829›Full record

ArticleMolecules (Basel, Switzerland)2025

Development and Validation of an LC-MS/MS Method for the Quantification of Methenamine in Raw Milk and Bovine Muscle and Its Application to Incurred Samples.

Sunjin Park, Chung-Oui Hong, Se-Hyung Kim, Seon-Young Lee, Inhae Jeon, Do Hui Kim, Hyun-Ok Ku, Mi-Young Park

Abstract readValidation Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunjin ParkVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0002-9553-5133
Chung-Oui HongVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0001-9233-737X
Se-Hyung KimVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0003-4747-7394
Seon-Young LeeVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0002-3523-4945
Inhae JeonVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0002-0437-2165
Do Hui KimVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0009-0003-4553-5703
Hyun-Ok KuVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0002-7890-7919
Mi-Young ParkVeterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0001-8534-9620

Funding

Animal and Plant Quarantine Agency M-1543073-2025-27-01
6 · The paper itself

Abstract

Methenamine, a urinary antiseptic with antimicrobial properties, decomposes into toxic formaldehyde under acidic conditions. Its use is prohibited in dairy cattle in Korea to prevent harmful residues in milk. This study was designed to develop and validate a sensitive and reliable LC-MS/MS method for determining methenamine in raw milk and bovine muscle in compliance with the Positive List System (PLS) regulations. Samples were extracted with acetonitrile (ACN)-methanol (MeOH) (7:3,

Indexed as

CattleLiquid Chromatography-Mass SpectrometryMethenamineMilkMusclesAnimalsMethenaminebovine muscleLC–MS/MSmethenaminePositive List System (PLS)raw milkresidue analysis

Identifiers

PMID41471829
PMCPMC12735475

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.