ArticleMolecules (Basel, Switzerland)2025
Rapid Chromatographic and Spectroscopic Analysis of Extracted Raw Propolis.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Preparation and Characterization of Propolis-Biopolymer Coatings on Textiles for Topical Applications: Chemical Composition, Bioactivity, and Cytotoxicity Assessment.Molecules (Basel, Switzerland) · 2026Article
- Propolis: A Natural Bioactive Compound with Emerging Roles in Functional Food Applications.International journal of molecular sciences · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Propolis is a complex mixture of natural compounds, including resinous terpenoids, flavonoids, aromatic acids, and essential oils, and has strong antimicrobial, antifungal, and antioxidant properties. The chemical composition of propolis determines its properties and strongly depends on a wide variety of different plant sources, as well as other climate and environmental parameters. In order to determine the main compounds, in this study, we applied an integrated analysis of propolis by thin-layer chromatography (TLC) to characterize and compare the phytochemical profiles of selected bioactive materials in raw propolis. TLC served as a rapid, cost-effective, and highly visual technique to separate and identify key constituents, including terpenoids, flavonoids, and phenolic compounds in propolis, without a need for further precleaning steps after performing ultrasonic extraction. Complementary methods, such as FTIR spectroscopy, were employed to validate and quantify the active components detected through TLC screening. In addition, the UV-VIS method revealed the solubility of raw propolis in different solvents, after testing for coffee ring effects. The results confirmed that the complex structure of the raw sample can be more thoroughly revealed by two-dimensional TLC, which enables not only rapid and verifiable qualitative results but also detection of overlapping spots. Moreover, by comparing the results with data from the literature, not only can particular chemical compounds be efficiently determined by TLC but also the regional origin of samples.
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Registered trials
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