Evidence map›Paper›PMID 41471386›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process.

Rolan R Shaifutdinov, Maria V Sinegubova, Ivan I Vorobiev, Polina E Prokhorova, Alexey B Podkorytov, Nadezhda A Orlova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rolan R ShaifutdinovLaboratory of Mammalian Cell Bioengineering, Skryabin Institute of Bioengineering, Federal State Institution, "Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences", 60 let Oktjabrja pr-t 7, bld. 1, 117312 Moscow, Russia.ORCID 0009-0007-5118-5067
Maria V SinegubovaLaboratory of Mammalian Cell Bioengineering, Skryabin Institute of Bioengineering, Federal State Institution, "Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences", 60 let Oktjabrja pr-t 7, bld. 1, 117312 Moscow, Russia.ORCID 0000-0002-8950-6061
Ivan I VorobievLaboratory of Mammalian Cell Bioengineering, Skryabin Institute of Bioengineering, Federal State Institution, "Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences", 60 let Oktjabrja pr-t 7, bld. 1, 117312 Moscow, Russia.ORCID 0000-0003-0064-4458
Polina E ProkhorovaMedsintez Plant LLC, Kirova 28, 620028 Ekaterinburg, Russia.
Alexey B PodkorytovMedsintez Plant LLC, Kirova 28, 620028 Ekaterinburg, Russia.
Nadezhda A OrlovaLaboratory of Mammalian Cell Bioengineering, Skryabin Institute of Bioengineering, Federal State Institution, "Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences", 60 let Oktjabrja pr-t 7, bld. 1, 117312 Moscow, Russia.ORCID 0000-0001-9483-2892

Funding

Institute of Bioengineering, FRCC "Fundamentals of Biotechnology"Plant Medsintezis LLC, partial funding not disclosed
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biosimilarCHO cellsdulaglutidefed-batchGLP-1-Fcin vitro bioactivitytransgene amplification

Identifiers

PMID41471386
PMCPMC12736101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.