ArticlePharmaceuticals (Basel, Switzerland)2025
An Ongoing Search for Multitarget Ligands as Potential Agents for Diabetes Mellitus and Its Long-Term Complications: New Insights into (5-Arylidene-4-oxothiazolidin-3-yl)alkanoic Acid Derivatives.
Rosanna Maccari, Rosaria Ottanà, Valerij Talagayev, Roberta Moschini, Francesco Balestri, Francesca Felice, Francesca Iannuccilli, Gemma Sardelli, Rebecca Sodano, Gerhard Wolber and 2 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
12 authors.
Rosanna MaccariDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0001-7561-737X Rosaria OttanàDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-5950-3230 Valerij TalagayevMolecular Design Group, Institute of Pharmacy, Freie Universität Berlin, Königin-Luisestr. 2 + 4, 14195 Berlin, Germany.ORCID 0000-0002-1907-9594 Roberta MoschiniBiochemistry Unit, Department of Biology, University of Pisa, via S. Zeno, 51, 56123 Pisa, Italy.ORCID 0000-0001-5227-2348 Francesco BalestriBiochemistry Unit, Department of Biology, University of Pisa, via S. Zeno, 51, 56123 Pisa, Italy.
Francesca FeliceBiochemistry Unit, Department of Biology, University of Pisa, via S. Zeno, 51, 56123 Pisa, Italy.ORCID 0000-0001-8968-2228 Francesca IannuccilliDepartment of Scienze Biomediche Sperimentali e Cliniche, Sezione di Scienze Biochimiche, University of Firenze, Viale Morgagni 50, 50134 Firenze, Italy.ORCID 0009-0008-4305-3619 Gemma SardelliBiochemistry Unit, Department of Biology, University of Pisa, via S. Zeno, 51, 56123 Pisa, Italy.ORCID 0000-0002-3617-0496 Rebecca SodanoDepartment of Scienze Biomediche Sperimentali e Cliniche, Sezione di Scienze Biochimiche, University of Firenze, Viale Morgagni 50, 50134 Firenze, Italy.ORCID 0009-0005-7819-1796 Gerhard WolberMolecular Design Group, Institute of Pharmacy, Freie Universität Berlin, Königin-Luisestr. 2 + 4, 14195 Berlin, Germany.ORCID 0000-0002-5344-0048 Paolo PaoliDepartment of Scienze Biomediche Sperimentali e Cliniche, Sezione di Scienze Biochimiche, University of Firenze, Viale Morgagni 50, 50134 Firenze, Italy.ORCID 0000-0001-6448-7266 Antonella Del CorsoBiochemistry Unit, Department of Biology, University of Pisa, via S. Zeno, 51, 56123 Pisa, Italy.ORCID 0000-0003-3165-6128 Funding
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6 · The paper itselfAbstract
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Indexed as
diabetes mellitusenzyme inhibitionin silico studiesmultitarget ligandsstructure-activity relationships
Identifiers
PMID41471352
PMCPMC12735461
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