Evidence map›Paper›PMID 41471278›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Protein Levels of 16 Cytochrome P450s and 2 Carboxyl Esterases Using Absolute Quantitative Proteomics: CYP2C9 and CYP3A4 Are the Most Abundant Isoforms in Human Liver and Intestine, Respectively.

Alexia Grangeon, Matthew L Arwood, David Thacker, Fleur Gaudette, Jacques Turgeon, Veronique Michaud

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexia GrangeonCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 St. Denis Street, Montréal, QC H2X 0A9, Canada.ORCID 0000-0002-6240-6693
Matthew L ArwoodGalenusRx Inc., P.O. Box 560025, Montverde, FL 34756, USA.ORCID 0000-0003-4737-9786
David ThackerGalenusRx Inc., P.O. Box 560025, Montverde, FL 34756, USA.
Fleur GaudetteCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 St. Denis Street, Montréal, QC H2X 0A9, Canada.ORCID 0000-0003-0453-1522
Jacques TurgeonGalenusRx Inc., P.O. Box 560025, Montverde, FL 34756, USA.ORCID 0000-0002-7978-9280
Veronique MichaudCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 St. Denis Street, Montréal, QC H2X 0A9, Canada.ORCID 0000-0002-1399-6447

Funding

CIHR #299309
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cryopreserved human intestinal mucosaCYP450human hepatocyteshuman intestinal mucosahuman liver microsomespharmacokinetic-pharmacodynamic modelingproteomics

Identifiers

PMID41471278
PMCPMC12735975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.