Evidence map›Paper›PMID 41471213›Full record

ArticlePathogens (Basel, Switzerland)2025

Hidden Circulation and Socio-Sanitary Vulnerability: Rotavirus A and Human Adenovirus Prevalence in Symptomatic and Asymptomatic Children in Central Brazil Post-COVID-19.

Jordana Gomes Paulino, Amanda de Oliveira Matos, Yasmin Gomes Passos, Fernanda Franco, Fabiola Souza Fiaccadori, Helioswilton Sales-Campos, Adriana Luchs, Menira Souza, Marcelle Silva-Sales

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jordana Gomes PaulinoLaboratory of Virology and Cellular Culture, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Rua 235, S/N, Setor Leste Universitário, Goiânia 746050-050, GO, Brazil.
Amanda de Oliveira MatosLaboratory of Mucosal Immunology and Immunoinformatics, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-220, GO, Brazil.
Yasmin Gomes PassosLaboratory of Virology and Cellular Culture, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Rua 235, S/N, Setor Leste Universitário, Goiânia 746050-050, GO, Brazil.
Fernanda FrancoLaboratory of Virology and Cellular Culture, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Rua 235, S/N, Setor Leste Universitário, Goiânia 746050-050, GO, Brazil.ORCID 0000-0002-8214-5283
Fabiola Souza FiaccadoriLaboratory of Virology and Cellular Culture, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Rua 235, S/N, Setor Leste Universitário, Goiânia 746050-050, GO, Brazil.ORCID 0000-0002-4100-8872
Helioswilton Sales-CamposLaboratory of Mucosal Immunology and Immunoinformatics, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia 74605-220, GO, Brazil.ORCID 0000-0003-3252-2834
Adriana LuchsAdolfo Lutz Institute, São Paulo 01246, SP, Brazil.ORCID 0000-0003-4131-990X
Menira SouzaLaboratory of Virology and Cellular Culture, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Rua 235, S/N, Setor Leste Universitário, Goiânia 746050-050, GO, Brazil.ORCID 0000-0003-3145-1376
Marcelle Silva-SalesLaboratory of Virology and Cellular Culture, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Rua 235, S/N, Setor Leste Universitário, Goiânia 746050-050, GO, Brazil.ORCID 0000-0002-4275-9627

Funding

São Paulo Research Foundation (FAPESP) #2015/12944-9São Paulo Research Foundation (FAPESP) #2020/14786-0The National Council for Scientific and Technological Development (CNPq) #430181/2018-3
6 · The paper itself

Abstract

Acute Diarrheal Disease (ADD) remains a major global health concern, with rotavirus A (RVA) and human adenovirus (HAdV) as key viral agents. This study evaluated the positivity rate and molecular characterization of RVA and HAdV in fecal samples from 114 children (0-5 years) in Goiás, Brazil, between January 2022 and December 2023, following the COVID-19 public health emergency. RVA was detected in 13.1% of samples (genotypes G1 and G6 associated with P[8]) and HAdV in 15.8% (genotypes A31, B3, C1, and C6), with two coinfection cases also being detected (1.7%). RVA predominated in unvaccinated 0-to-6-month-old children, while most asymptomatic cases occurred among vaccinated children. HAdV was also mainly identified in this age group, including asymptomatic children. Viral positivity was more common among children without access to treated water. In conclusion, this study underscores the ongoing circulation and genetic diversity of RVA and HAdV among children in Goiás in the post-pandemic period. The findings highlight the influence of vaccination coverage and sanitation on viral positivity, emphasizing the need for integrated public health strategies. Continuous molecular surveillance remains essential to detect emerging genotypes and guide effective prevention and control measures against ADD.

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanCOVID-19DiarrheaRotavirusRotavirus InfectionsBrazilChild, PreschoolCoinfectionFecesFemaleGenotypeHumansInfantInfant, NewbornMaleAcute Diarrheal Diseasehuman adenovirusrotavirus Asocio-sanitary vulnerabilityviral hidden circulation

Identifiers

PMID41471213
PMCPMC12735434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.