Evidence map›Paper›PMID 41471173›Full record

ArticlePathogens (Basel, Switzerland)2025

Nisin or Chitosan Enhance the Antimicrobial Activity of Ceftiofur Against Antibiotic-Resistant

Mónica G Sánchez-Ceja, Jaime L Esquivel-Alejo, Ricardo I Medina-Estrada, Rafael Jiménez-Mejía, Gustavo Santoyo, Joel E López-Meza, Pedro D Loeza-Lara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mónica G Sánchez-CejaFoods Genomics, Universidad de La Ciénega del Estado de Michoacán de Ocampo (UCEMICH), Sahuayo 59103, Mexico.
Jaime L Esquivel-AlejoFoods Genomics, Universidad de La Ciénega del Estado de Michoacán de Ocampo (UCEMICH), Sahuayo 59103, Mexico.
Ricardo I Medina-EstradaFoods Genomics, Universidad de La Ciénega del Estado de Michoacán de Ocampo (UCEMICH), Sahuayo 59103, Mexico.ORCID 0000-0001-7038-1724
Rafael Jiménez-MejíaFoods Genomics, Universidad de La Ciénega del Estado de Michoacán de Ocampo (UCEMICH), Sahuayo 59103, Mexico.
Gustavo SantoyoGenomic Diversity Laboratory, Institute of Chemical and Biological Research, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Mexico.ORCID 0000-0002-0374-9661
Joel E López-MezaMultidisciplinary Center for Biotechnology Studies, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58893, Mexico.ORCID 0000-0002-3269-9202
Pedro D Loeza-LaraFoods Genomics, Universidad de La Ciénega del Estado de Michoacán de Ocampo (UCEMICH), Sahuayo 59103, Mexico.ORCID 0000-0002-7953-5723

Funding

SECIHTI CF-2023-I-1277Universidad de la Ciénega UCEMICH/SAC/547/08/22
6 · The paper itself

Abstract

Mastitis is one of the major diseases affecting dairy cattle worldwide. Antibiotic therapy remains the most widely used treatment. However, its effectiveness has been compromised due to the selection of antibiotic-resistant and biofilm-producing pathogenic bacteria. This promotes the search for alternatives that increase the antibacterial and antibiofilm efficacy of antibiotics such ceftiofur (CFT). Nisin (N) and chitosan (CH) may possess these properties. The aim of this study was to evaluate whether N + CFT and CH + CFT combinations enhance the antibacterial activity of the antibiotic on

Indexed as

Anti-Bacterial AgentsBiofilmsCephalosporinsChitosanNisinStaphylococcus aureusAnimalsCattleDrug Resistance, BacterialDrug SynergismFemaleMastitis, BovineMicrobial Sensitivity TestsStaphylococcal InfectionsAnti-Bacterial AgentsceftiofurCephalosporinsChitosanNisinantibiotic enhancersantibiotic resistanceceftiofurchitosannisinStaphylococcus aureus

Identifiers

PMID41471173
PMCPMC12736378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.