Evidence map›Paper›PMID 41471155›Full record

ReviewPathogens (Basel, Switzerland)2025

The Paradox of Healthcare in the 'Superbugs' Era: Current Challenges and Future Directions.

Elenoire Sole, Marilena Trinchera, Silvia De Gaetano, Angelina Midiri, Giovanni Piccolo, Giuseppe Mancuso, Giovanni Schepici, Carmelo Biondo

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elenoire SoleDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.
Marilena TrincheraDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.
Silvia De GaetanoDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.
Angelina MidiriDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.
Giovanni PiccoloDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.
Giuseppe MancusoDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-5454-3228
Giovanni SchepiciIRCCS Centro Neurolesi Bonino Pulejo, 98124 Messina, Italy.
Carmelo BiondoDepartment of Human Pathology, University of Messina, 98125 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic-resistant microbes represent a growing problem for modern medicine and public health. Projections indicate that deaths from such infections could reach 10 million per year by 2050. Healthcare associated infections (HAI) are among the most significant causes of mortality and morbidity in hospitals, impacting millions of patients globally. The emergence of HAI is associated with resistance to antimicrobials, rapidly worsening the patient's condition. Antimicrobial resistance determines unresponsiveness to treatment, which can ultimately lead to severe complications such as sepsis and shock. It is estimated that one in every ten patients are susceptible to infection during their stay in hospital, with the microorganism responsible for the infection frequently proving resistant to antibiotics. Among the latter, CRE (carbapenem-resistant

Indexed as

Bacterial InfectionsCross InfectionDrug Resistance, Multiple, BacterialAnti-Bacterial AgentsHumansIncidenceAnti-Bacterial AgentsAMRhospital-acquired infections (HAI)MDRsuperbugs

Identifiers

PMID41471155
PMCPMC12736082

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.