Evidence map›Paper›PMID 41471151›Full record

ArticlePathogens (Basel, Switzerland)2025

A Novel, Broad-Spectrum, Virulent Bacteriophage Targeting

Ying Long, Youhong Zhong, Pan Liu, Chunpeng Mao, Haipeng Zhang, Liyuan Shi, Shaogui Zi, Xinyu Qin, Zongti Shao, Rongji Cao and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Abundance ofPathogens (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ying LongDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali University, Dali 671003, China.
Youhong ZhongYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Pan LiuYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Chunpeng MaoYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Haipeng ZhangYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Liyuan ShiYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.ORCID 0000-0001-5065-7543
Shaogui ZiYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Xinyu QinYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Zongti ShaoYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Rongji CaoYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Hongbaiyu LiuYunnan Pu'er Medical School, Pu'er 665099, China.ORCID 0009-0005-1312-1762
Qingwen GaoSchool of Public Health, Dali University, Dali 671003, China.
Ling YangYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.
Yuming ChenDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali University, Dali 671003, China.
Yuanying ShenDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali University, Dali 671003, China.
Peng WangYunnan Key Laboratory for Zoonosis Control and Prevention, Yunnan Institute for Endemic Disease Control and Prevention, Dali 671000, China.ORCID 0000-0002-3350-1835

Funding

National Natural Science Foundation of China 32260039the Dali University Scientific Research Development Fund FZ2023ZD019the Yunnan Provincial High-Level Health Technology Talent Training Program L-2019001the Yunnan Provincial Technological Innovation Talent Training Program 202305AD160011
6 · The paper itself

Abstract

As promising biological tools, bacteriophages offer broad potential applications in disease diagnosis, treatment, and food safety. This study is the first to isolate a novel bacteriophage, designated vB_YpP_JC53 (abbreviated JC53), from the soil of wild rodent nests in plague-endemic areas of Yunnan Province. This bacteriophage is a T7-like phage that has the broadest host range among all T7-like phages discovered to date and remains stable under varying temperature and pH conditions. Comparative genomic analysis through NCBI revealed that the nucleotide sequence of phage JC53 shares 94.98% homology (95% coverage) with phage PSTCR2, a member of the

Indexed as

BacteriophagesRodentiaSoil MicrobiologyYersinia pestisAnimalsChinaGenome, ViralHost SpecificityPhylogenyPlaguebroad-spectrum activitygenomic characteristicsnovel bacteriophagestrong lytic activityYersinia pestis

Identifiers

PMID41471151
PMCPMC12735813

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.