Evidence map›Paper›PMID 41471150›Full record

ArticlePathogens (Basel, Switzerland)2025

High Seroprevalence of Feline Leishmaniosis (FeL) in Campania (Italy) Region: Current Epidemiological Scenario.

Valentina Foglia Manzillo, Ines Balestrino, Gaetano Oliva, Roberta Brunetti, Stefania Cavallo, Rosa D'Ambrosio, Roberta Pellicanò, Luisa Spadari, Lorella Barca, Federica Bruno and 6 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Valentina Foglia ManzilloDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.
Ines BalestrinoDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.
Gaetano OlivaDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.
Roberta BrunettiExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.ORCID 0000-0003-1597-9322
Stefania CavalloExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.ORCID 0000-0001-5695-8005
Rosa D'AmbrosioExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.ORCID 0000-0001-6172-3446
Roberta PellicanòExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.ORCID 0000-0001-8416-996X
Luisa SpadariExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.
Lorella BarcaExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.ORCID 0009-0000-4513-0018
Federica BrunoNational Reference Center for Leishmaniosis (C.Re.Na.L.), OIE Leishmania Reference Laboratory, Experimental Zooprophylactic Institutes of Sicily (IZS Sicilia), Via Gino Marinuzzi 3, 90129 Palermo, Italy.ORCID 0000-0001-6181-6984
Maria Ortensia MontellaDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.ORCID 0009-0000-8391-9255
Maria Paola MaurelliDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.ORCID 0000-0002-7564-3356
Nunzia FlorindoLocal Health Authority (ASL) Napoli 3 Sud, U.O.S. Clinica Veterinaria, Via Calastro 26, 80059 Torre del Greco, Italy.
Manuela GizzarelliDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.ORCID 0000-0002-3362-5395
Mariele De SantiDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80137 Naples, Italy.ORCID 0000-0003-0466-5563
Loredana BaldiExperimental Zooprophylactic Institute of Southern Italy (IZSM), Via Salute 2, 80055 Portici, Italy.ORCID 0000-0003-3087-7148

Funding

PROGETTI DI RICERCA CORRENTE 2021 IZS ME 20-21 RC
6 · The paper itself

Abstract

Feline leishmaniosis (FeL) is still considered an emerging and neglected disease. Cats, once considered accidental hosts, are now recognized as adjunctive reservoirs of the disease, especially in areas where canine (CanL) and human (HumL) leishmaniosis are widespread. Although often asymptomatic, infected cats could contribute to the transmission cycle of the parasite. Recent studies in Campania (Italy) have found a significant prevalence of feline infection, indicating the need to implement diagnostic and surveillance protocols to prevent the spread of the disease. The aim of the study was to outline the current scenario by studying the prevalence of FeL in Campania to identifying the potential zoonotic risk and in addition to validate the Immunofluorescence Antibody Test (IFAT) method for the diagnosis of leishmaniosis in cats. The study involved initially 702 cats; for each cat, a clinical record was compiled, including identification data, anamnesis, and clinical findings. Due to incomplete information, statistical analysis was performed only on a subset of 601 cats. A blood sample was collected to obtain serum/plasma specimens. When feasible, a lymph node fine-needle aspiration was performed. The observed seroprevalence rate was 32.1% (193/601), with a higher seroprevalence in outdoor cats and the presence of asymptomatic seropositive animals (28.0%;54/193), suggesting that felines may act as silent reservoirs of

Indexed as

Antibodies, ProtozoanCat DiseasesLeishmaniasisAnimalsCatsFemaleFluorescent Antibody Technique, IndirectItalyLeishmania infantumMaleSeroepidemiologic StudiesAntibodies, ProtozoancatepidemiologyIFATleishmania

Identifiers

PMID41471150
PMCPMC12735749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.