Evidence map›Paper›PMID 41471138›Full record

ArticlePharmaceutics2025

Selection of Solubility Enhancement Technologies for S-892216, a Novel COVID-19 Drug Candidate.

Ryo Ohashi, Shuichi Otake, Tatsuhiko Murata, Ryosuke Watari, Shinpei Yoshida, Mikiko Kitade, Daisuke Kondo, Go Kimura

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryo OhashiFormulation R&D Laboratory, Pharmaceutical Technology Research Division, Shionogi & Co., Ltd., 1-3 Kuise, Terajima 2-chome, Amagasaki 660-0813, Japan.ORCID 0009-0000-5119-099X
Shuichi OtakeFormulation R&D Laboratory, Pharmaceutical Technology Research Division, Shionogi & Co., Ltd., 1-3 Kuise, Terajima 2-chome, Amagasaki 660-0813, Japan.
Tatsuhiko MurataFormulation R&D Laboratory, Pharmaceutical Technology Research Division, Shionogi & Co., Ltd., 1-3 Kuise, Terajima 2-chome, Amagasaki 660-0813, Japan.
Ryosuke WatariLaboratory for Drug Discovery and Development, Shionogi & Co., Ltd., 1-1 Futaba-cho 3-chome, Toyonaka 561-0825, Japan.ORCID 0009-0004-1846-0467
Shinpei YoshidaLaboratory for Drug Discovery and Development, Shionogi & Co., Ltd., 1-1 Futaba-cho 3-chome, Toyonaka 561-0825, Japan.
Mikiko KitadeLaboratory for Drug Discovery and Development, Shionogi & Co., Ltd., 1-1 Futaba-cho 3-chome, Toyonaka 561-0825, Japan.
Daisuke KondoFormulation R&D Laboratory, Pharmaceutical Technology Research Division, Shionogi & Co., Ltd., 1-3 Kuise, Terajima 2-chome, Amagasaki 660-0813, Japan.
Go KimuraFormulation R&D Laboratory, Pharmaceutical Technology Research Division, Shionogi & Co., Ltd., 1-3 Kuise, Terajima 2-chome, Amagasaki 660-0813, Japan.

Funding

Japan Agency for Medical Research and Development JP21fk0108584Japan Agency for Medical Research and Development JP22fk0108522h0001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amorphous solid dispersionoral solutionpoorly water-soluble drugsolubility enhancement technologystability

Identifiers

PMID41471138
PMCPMC12737236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.