Evidence map›Paper›PMID 41471106›Full record

ArticlePharmaceutics2025

Towards Personalized Lymphodepletion: A Population Pharmacokinetic Fludarabine Model in Patients Receiving CAR T-Cell Therapy.

Javier Varela-González-Aller, Mario Andrés Sánchez-Salinas, Iñaki Troconiz, Gloria Iacoboni, Carla Alonso-Martínez, Maria-Josep Carreras-Soler, Cecilia Carpio, Anna Farriols-Danes, María Guerra-González, Alfredo Rivas-Delgado and 5 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Javier Varela-González-AllerPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0009-0006-9606-4405
Mario Andrés Sánchez-SalinasHematology Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0009-0004-2301-1367
Iñaki TroconizPharmacometrics and Systems Pharmacology Research Unit, Department of Pharmaceutical Sciences, School of Pharmacy and Nutrition, University of Navarra, Pharmacy, Campus Universitario, 31009 Pamplona, Spain.ORCID 0000-0003-3700-8658
Gloria IacoboniHematology Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0000-0003-0805-9288
Carla Alonso-MartínezPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0000-0003-0032-4059
Maria-Josep Carreras-SolerPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0000-0001-6482-9940
Cecilia CarpioHematology Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.
Anna Farriols-DanesPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.
María Guerra-GonzálezPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.
Alfredo Rivas-DelgadoHematology Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.
Lucas Rivera SanchezPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0000-0002-1875-9512
Samantha FeijooHematology Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.ORCID 0009-0001-8591-552X
Carolina ValdiviaPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.
Pere BarbaHematology Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.
Marta MiaronsPharmacy Department, Vall D'Hebron University Hospital, Pg. de la Vall d'Hebron, 119, Horta-Guinardó, 08035 Barcelona, Spain.

Funding

Instituto de Salud Carlos III PI21/00197 and INT23/00072
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

fludarabinenon-Hodgkin lymphomapharmacokineticspopulation pharmacokinetic model

Identifiers

PMID41471106
PMCPMC12736365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.