Evidence map›Paper›PMID 41471097›Full record

ArticlePharmaceutics2025

Pharmacokinetics of CYP2C19- and CYP3A4-Metabolized Drugs in Cirrhosis Using a Whole-Body PBPK Approach.

Ruijing Mu, Jingjing Gao, Xiaoli Wang, Jing Ling, Nan Hu, Hanyu Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruijing MuCenter of Drug Metabolism and Pharmacokinetics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Jingjing GaoCenter of Drug Metabolism and Pharmacokinetics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Xiaoli WangMianzhu Municipal Health Bureau, Deyang 618200, China.
Jing LingDepartment of Pharmacy, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.
Nan HuDepartment of Pharmacy, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.ORCID 0000-0002-7505-5001
Hanyu YangCenter of Drug Metabolism and Pharmacokinetics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.

Funding

National Natural Science Foundation of China Nos. 82204511the "Double First-Class" university project No. CPU2022QZ21Top Talent of Changzhou"The 14th Five-Year Plan" High-Level Health Talents Training Project 2022CZBJ042
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CYP2C19CYP3A4dose optimizationliver cirrhosispharmacokineticsphysiologically based pharmacokinetic model

Identifiers

PMID41471097
PMCPMC12737180

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.