Metabolic and Neuroenergetic Effects of Intranasal Vitamin C Application in the Human Brain.

Lena-Christin Ingwersen, Alina Kistenmacher, Uwe H Melchert, Kerstin M Oltmanns

Abstract readRandomized Controlled Trial

In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lena-Christin IngwersenSection of Psychoneurobiology, Center of Brain, Behavior and Metabolism, University of Luebeck, 23562 Luebeck, Germany.ORCID 0009-0004-5418-8333

Alina KistenmacherSection of Psychoneurobiology, Center of Brain, Behavior and Metabolism, University of Luebeck, 23562 Luebeck, Germany.

Uwe H MelchertSection of Psychoneurobiology, Center of Brain, Behavior and Metabolism, University of Luebeck, 23562 Luebeck, Germany.

Kerstin M OltmannsSection of Psychoneurobiology, Center of Brain, Behavior and Metabolism, University of Luebeck, 23562 Luebeck, Germany.

Funding

German Research Foundation (DFG) Transregional Collaborative Research Center 134

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ascorbic AcidBrainEnergy MetabolismObesityAdenosine TriphosphateAdministration, IntranasalAdultBlood GlucoseEatingHumansInsulinMalePhosphocreatineYoung AdultAdenosine TriphosphateAscorbic AcidBlood GlucoseInsulinPhosphocreatineadenosine triphosphate (ATP)ascorbic acidcerebral high-energy phosphatesglucose metabolisminsulin resistanceneuroprotectiveobesityphosphocreatine (PCr)

Identifiers

PMID41470820

DOI10.3390/nu17243875

PMCPMC12735636

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.