Evidence map›Paper›PMID 41470796›Full record

ArticleNutrients2025

Wenjun Zhu, Paba Edirisuriya, Qing Ai, Fei Yang, Jiangqi Tang, Kai Nie, Xiangming Ji, Samira Soltanieh, Maesha Musarrat, Md Abdul Alim and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenjun ZhuDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Paba EdirisuriyaDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Qing AiDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.ORCID 0000-0002-2739-8261
Fei YangDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Jiangqi TangDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Kai NieDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Xiangming JiDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Samira SoltaniehDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Maesha MusarratDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.
Md Abdul AlimDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.ORCID 0000-0002-7222-0032
Zerui LiaoDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.ORCID 0009-0002-4917-2332
Kequan ZhouDepartment of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated the potential beneficial effects of a probiotic candidate,

methodsC57BL/6 DIO mice were assigned to three groups (ad libitum): standard low-fat control (LF, 10% fat), high-fat diet (HF, 60% fat), and high-fat diet supplemented with approximately one billion CFU/day of CC2316 via daily oral gavage for 16 weeks.

resultsAfter 16 weeks, the CC group exhibited 17.3% lower body weight gain (

conclusionsThis investigation strongly suggests that CC2316 supplementation mitigates the adverse effects of HFD-induced obesity by modulating whole-body energy metabolism, positioning it as a potential aid to lower risk factors associated with metabolic syndrome. The precise mechanisms linking the gut microbiome to altered energy substrate utilization are discussed and suggested for further investigation.

Indexed as

Blood GlucoseDiet, High-FatEnergy MetabolismMetabolic SyndromeObesityProbioticsAnimalsHomeostasisInsulinInsulin ResistanceMaleMiceMice, Inbred C57BLRisk FactorsBlood GlucoseInsulinbody weight gainC. cochleariumdietary supplementationenergy expenditureglucose homeostasisgut microbiomehigh-fat diet

Identifiers

PMID41470796
PMCPMC12736123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.