ReviewPlants (Basel, Switzerland)2025
Plant Responses to Heavy Metal Stresses: Mechanisms, Defense Strategies, and Nanoparticle-Assisted Remediation.
Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Integrating pharmacologically important flora into phytoremediation: The role of bacillus strains in mitigating chromium toxicity and enhancing rhizostabilization.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Narrative Review of Nanomaterial Interactions in Plants with a Focus on Multi-Omics and Epigenetic Remodeling.Plants (Basel, Switzerland) · 2026Review
- Mineral Accumulation and Physiological Responses of Two Halophytes,Plants (Basel, Switzerland) · 2026Article
- Mechanistic insights into organic acid-mediated mitigation of nickel toxicity in maize (Zea mays L.) grown on mining-impacted soils.BMC plant biology · 2026Article
- Article
- A review of toxicity and remediation: thorium uptake by woody plants.Biodegradation · 2026Review
- Article
- Integrated physiological, biochemical, and transcriptomic analyses reveal lead-induces stress responses and tolerance of bread wheat (Triticum aestivum L.).BMC plant biology · 2026Article
- From Abiotic Stress to Emerging Environmental Pollutants: Expanding Roles of Melatonin and NO in Plant Defense.International journal of molecular sciences · 2026Review
- Species-Specific Effects of Humic Substances and Mycorrhiza on Antioxidant Defense and Metal Stress Tolerance inInternational journal of molecular sciences · 2026Article
- Integrated Biochemical and Ultrastructural Responses ofPlants (Basel, Switzerland) · 2026Article
- Invasive Plants as Accumulators of Heavy Metals and Potentially Toxic Elements: A Review with Implications for Remediation.Plants (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heavy metal (HM) contamination threatens environmental sustainability, food safety, and agricultural productivity worldwide. HM toxicity adversely affects plant growth, reducing germination rates by 20-50%, impairing seedling establishment, and inhibiting shoot and root development by 30-60% in various crops. HM disrupts key physiological processes, including photosynthesis, stomatal regulation, membrane integrity, nutrient uptake, and enzymatic and nonenzymatic antioxidant activities. These disruptions largely result from oxidative stress, caused by the excessive accumulation of reactive oxygen species, which damage cellular components. To counteract HM toxicity, plants deploy a complex defense network involving antioxidant enzymes, metal chelation by phytochelatins and metallothioneins, vacuolar sequestration, and symbiotic interactions with arbuscular mycorrhizal fungi, which can retain 40-70% of metals in roots and reduce translocation to shoots. At the molecular level, MAPK (Mitogen-Activated Protein Kinase) signaling pathways, transcription factors (e.g., WRKY, MYB, bZIP, and NAC), and phytohormonal crosstalk regulate the expression of stress-responsive genes expression to enhance HM stress tolerance. Advances in nanotechnology offer promising strategies for the remediation of HM-contaminated soils and water sources (HM remediation); engineered and biogenic nanoparticles (e.g., ZnO, Fe
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.