Evidence map›Paper›PMID 41470545›Full record

ArticleMicromachines2025

Small Object Localization with 90% Annotation Reduction by Positive-Unlabeled Learning.

Xiao Zhou, Shihong Wang, Weiguo Hu, Zhaohao Xie, Zheng Pang, Zhuo Jiang, Zhen Cheng

Abstract read
In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao ZhouDepartment of Automation, Tsinghua University, Beijing 100084, China.
Shihong WangSchool of Biomedical Engineering, Tsinghua University, Beijing 100084, China.
Weiguo HuDepartment of Automation, Tsinghua University, Beijing 100084, China.
Zhaohao XieSchool of Biomedical Engineering, Tsinghua University, Beijing 100084, China.
Zheng PangSchool of Biomedical Engineering, Tsinghua University, Beijing 100084, China.
Zhuo JiangCollege of Food Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-7975-7625
Zhen ChengDepartment of Automation, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-8197-5560

Funding

Beijing Natural Science Foundation 3242008China Postdoctoral Science Foundation 2023M741850National Natural Science Foundation of China 62103228National Natural Science Foundation of China 62571293Young Elite Scientists Sponsorship Program by CAST 2023QNRC001
6 · The paper itself

Abstract

Small object localization is one of the most challenging tasks owing to the poor visual appearance and noisy representation caused by the intrinsic structure of small targets. Recent advances in localizing small objects are mainly dependent on regression-based counting approaches, which require considerable annotations for training. As a contrast, human learners can quickly master labeling skills from only a few annotation examples. In this paper, we attempt to simulate this training mechanism and propose a novel positive-unlabeled (PU) learning based approach that can localize small objects by learning from partial point annotations. We evaluate our approach on five typical datasets of small objects involving a single cell, an animal/insect, and human crowds. Quantitative experimental results show that our approach has achieved inspiring localization performance (F1 score > 0.75) even under the supervision of less than 10% of the overall point annotations. This approach paves the way for low-annotation-cost single-cell analysis within microfluidic droplets.

Indexed as

localizationpoint annotationspositive-unlabeled (PU) learningsingle cellsmall object

Identifiers

PMID41470545
PMCPMC12735266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.