Evidence map›Paper›PMID 41469956›Full record

ArticleBMC neurology2025

Spontaneous Intracerebral Hemorrhage in young patients from a Comprehensive Stroke Care Unit in MENA region, Hospital Based Study.

Islam El-Malky, Hosam Alieldeen Abdelmageed, Hussein Bahey El-Deen, Mahmoud Abdelhafiz

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Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Islam El-MalkyDepartment of Neurology, Director of Interventional Neurovascular Unit, South Valley University, Qena, Egypt. islam.elmalky@yahoo.com.ORCID http://orcid.org/0000-0002-3092-2159
Hosam Alieldeen AbdelmageedDepartment of Neuropsychiatry, South Valley University, Qena, Egypt.
Hussein Bahey El-DeenDepartment of Neurology, South Valley University, Qena, Egypt.
Mahmoud AbdelhafizDepartment of Neuropsychiatry, South Valley University, Qena, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFew studies have been reported on ICH in young age patients at Middle East and North Africa region (MENA). It is thought that epidemiological, radiological characteristics, and neurological outcomes differ in young age patients from those of the elderly. Our study’s aim is detection of the difference between them as regard clinic-radiological characters, functional outcome, and its predictors.

methodsAll patients with spontaneous ICH were divided into two groups, young adults (≤ 50 years) and old adults group (> 50 years). All clinic-radiological data were collected. The patients were classified into four categories (probable CAA, Hypertensive, Vascular and Undetermined). One-month mortality and functional outcome (using mRS) were determined. Multivariate logistic regression was performed to determine the predictors of favorable functional outcome.

resultsProspective study was conducted on 300 patients, 91 patients of them were young (30.3%). Hypertension, Diabetes mellitus, Hyperlipidemia, previous CVS, higher NIHSS, lower GCS and previous medications of antiplatelet or anticoagulant were more common in old age group with statistically significant difference (P value: <0.001, < 0.001, < 0.001, 0.006, < 0.001, < 0.001 and < 0.001, respectively). Vascular cause and undetermined cause were more in young age. Young group had better outcome as regard functional outcome and one-month mortality (74.7% versus 35.9% with p value: <0.001, 8.8% versus 28.7% with p value: <0.001, respectively). GCS and NIHSS are predictors of functional outcome.

conclusionSpontaneous ICH in young adults has different demographic, clinical and radiological findings with better One-month mortality and favorable functional outcome. GCS and NIHSS are predictors of functional outcome.

Indexed as

Cerebral HemorrhageStrokeAdultAfrica, NorthernAgedAge FactorsFemaleHumansMaleMiddle AgedMiddle EastProspective StudiesCerebral Amyloid AngiopathyHypertensive HemorrhageSpontaneous ICHvascular

Identifiers

PMID41469956
PMCPMC12853566

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