Evidence map›Paper›PMID 41469944›Full record

ArticleBMC cardiovascular disorders2025

The association of social support with functional status and physical activity in patients with coronary heart disease from The Heart and Soul study.

Abdelaziz Elnaggar, Thomas J Hoffmann, Mary A Whooley, Rochelle Szuba, Linda G Park

Abstract readMulticenter Study
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdelaziz ElnaggarDepartment of Community Health Systems, School of Nursing, University of California San Francisco, San Francisco, CA, USA. abdelaziz.elnaggar@ucsf.edu.
Thomas J HoffmannInstitute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.
Mary A WhooleyDepartments of Medicine and Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Rochelle SzubaDepartment of Community Health Systems, School of Nursing, University of California San Francisco, San Francisco, CA, USA.
Linda G ParkDepartment of Community Health Systems, School of Nursing, University of California San Francisco, San Francisco, CA, USA.

Funding

Epidemiology of Depression and Heart Failure in AgingR01HL079235 · NHLBI · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WHOOLEY, MARY A · 2005 to 2009
$4.2M
NHLBI NIH HHS R01 HL079235
6 · The paper itself

Abstract

introductionCoronary heart disease (CHD) is a significant public health problem among older adults that is associated with reduced physical activity (PA) and impaired functional capacity, commonly measured by activities of daily living (ADL) and instrumental activities of daily living (iADL). Maintaining independence in ADLs is critical for older adults' quality of life and healthcare outcomes. While social support is known to improve health outcomes, its long-term impact on PA and functional status in CHD patients has not been fully explored.

objectiveThis study aimed to investigate the association between social support and functional outcomes, including PA, in a cohort of long-term survivors with established CHD.

methodsThis study leverages 2 decades of the Heart and Soul Study, a multicenter investigation into mental health factors and clinical outcomes in individuals with CHD. We report a longitudinal analysis of baseline (2000–2002) and 20-year follow-up data (2022) to detect differences in social support and its association with functional status and PA over 20 years of surviving participants. Social support was measured using the 12-item Interpersonal Support Evaluation List (ISEL) subscales. Functional status was assessed using a combination of Katz and Lawton ADL scales, and PA was measured with self-reported data. Logistic regression models assessed associations between social support, ADL, and PA, accounting for change over time (baseline and 20 years), adjusting for sociodemographic factors and depressive symptoms.

resultsThe sample included 129 participants (mean age 80.9 years, SD ± 9.1), 72.9% of whom were male. In unadjusted analyses, better appraisal and belonging social support scores were associated with greater independence in iADL. These associations were insignificant after adjusting for sociodemographic characteristics (age, sex, income, race/ethnicity) and depression. Better appraisal and belonging scores were also significantly associated with higher PA. These associations remained significant after adjusting for sociodemographic factors, but did not remain significant after controlling for depression. After adjusting for the same covariates, we found no significant interaction between social support and time (20 years).

conclusionThis study provides a 20-year perspective on the role of social support in maintaining physical activity and independence in older adults with CHD. Our findings suggest that while social support is linked to better functional status and PA, these benefits are not sustained, accounting for sociodemographic characteristics and depression. Highlighting the need for integrating mental health support alongside social support strategies in long-term interventions to improve functional outcomes.

Indexed as

Activities of Daily LivingCoronary DiseaseExerciseFunctional StatusSocial SupportAgedAged, 80 and overAge FactorsFemaleHumansLongitudinal StudiesMaleMental HealthQuality of LifeRisk FactorsTime FactorsActivities of daily livingCoronary heart diseaseDepressionFunctional statusInstrumental activities of daily livingOlder adultsPhysical activitySocial support

Identifiers

PMID41469944
PMCPMC12754942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.