Evidence map›Paper›PMID 41469938›Full record

ArticleBMC genomics2025

Genomic characterization of Staphylococcus epidermidis Se252 isolated from the rhizosphere of a Brazilian endemic plant.

Angélica Bianchini Sanchez, Camila Gracyelle de Carvalho Lemes, Isabella Ferreira Cordeiro, Washington Luiz Caneschi, Érica Felestrino Barbosa, Camila Henriques de Paula, Ana Karla da Silva, Dilson Fagundes Ribeiro, Rosilene Cristina de Matos, Jéssica Pereira de Matos and 7 more

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In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Angélica Bianchini SanchezPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil. angelisanchez@gmail.com.
Camila Gracyelle de Carvalho LemesPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Isabella Ferreira CordeiroPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Washington Luiz CaneschiPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Érica Felestrino BarbosaPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Camila Henriques de PaulaPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Ana Karla da SilvaPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Dilson Fagundes RibeiroPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Rosilene Cristina de MatosPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Jéssica Pereira de MatosPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Lorrana Cachuite Mendes RochaPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Maria Rosilene Alves DamascenoPrograma de Pós-Graduação em Ciências Biológicas, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Camila Carrião Machado GarciaPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
João Carlos SetubalDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, SP, Brazil.
Alessandro de Mello VaraniFaculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP), Jaboticabal, SP, Brazil.
Nalvo Franco AlmeidaFaculdade de Computação, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Leandro Marcio MoreiraPrograma de Pós-Graduação em Biotecnologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil. lmmorei@gmail.com.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico LMM, NFA, JCS, AMVFundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-02357-17
6 · The paper itself

Abstract

backgroundStaphylococcus epidermidis (Se) is commonly regarded as a commensal organism; however, under specific conditions, it may act as an opportunistic pathogen. Here, we report the whole-genome sequencing and comparative genomic analysis of Se strain 252 (Se252), isolated from the rhizosphere of an endemic Brazilian plant.

resultsSe252 exhibits a unique repertoire of genes associated with environmental adaptation and virulence. These include two putative Type VII secretion system (T7SS) effectors and thirteen proteins involved in adhesion, toxin production, and immune evasion—among them, IsaB, which has not been previously reported in Se. Gene family expansions were observed in loci related to phenol-soluble modulins (PSMs), TLpps, LPXTG-motif proteins, nonribosomal peptide synthetases (NRPS), and siderophore biosynthesis (staphylopine, staphyloferrin), as well as quorum-sensing autoinducing peptides. In contrast, Se252 harbors relatively few antibiotic resistance genes.

conclusionsThe genomic profile of Se252 reflects adaptations to a plant-associated environment, yet harbors multiple features potentially enhancing human pathogenicity. These findings highlight the relevance of environmental Se lineages as possible reservoirs of virulence traits with implications for public health.

Indexed as

Genome, BacterialGenomicsRhizosphereStaphylococcus epidermidisBacterial ProteinsBrazilPhylogenyVirulenceVirulence FactorsBacterial ProteinsVirulence FactorsComparative genomicsEmerging pathogensHorizontal gene transferRhizosphereStaphylococcus epidermidisType VII secretion systemVirulence factors

Identifiers

PMID41469938
PMCPMC12865978

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.