ReviewBMC microbiology2025
The emerging tick-borne Yezo virus - current knowledge, challenges, and perspectives.
Review in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Targeted cleavage site mutations in the Gn precursor enable efficient generation of replication-competent rVSV-based surrogates for emerging nairoviruses.Emerging microbes & infections · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Ticks are external parasites that can carry and transmit a diverse range of pathogens, including bacteria, parasites, and viruses. In recent years, factors such as climate change, deforestation, and human activities have contributed to the expansion of tick populations along with the pathogens they harbour. These pathogens can cause serious disease in both humans and animals, such as Lyme disease and Crimean-Congo hemorrhagic fever (CCHF). In 2021, a novel tick-borne orthonairovirus, Yezo virus (YEZV) was reported in Hokkaido, Japan, in two patients presenting with acute febrile illness characterized by thrombocytopenia and leukopenia. Subsequent cases of YEZV have been reported in China, and it has been isolated in ticks collected from migratory birds in Japan, indicating its potential to spread further. As this virus emerges, critical gaps remain in understanding the mechanisms of YEZV pathogenesis, transmission, and prevention. This review aims to provide a comprehensive understanding of YEZV since its discovery, with a focus on its biology, pathogenesis, reported patient cases, treatments, and prevention strategies. By examining the current literature, this review seeks to identify key directions for future research and public health initiatives to enhance control measures for this emerging disease. Ultimately, adopting cross-sectoral One Health approaches will improve early warning, prevention, and preparedness for a potential global health emergency caused by YEZV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.