Evidence map›Paper›PMID 41469923›Full record

ReviewJournal of cardiothoracic surgery2025

Bibliometric and visual analysis of ferroptosis in cardiovascular diseases.

Xianghu Zhao, Xiaohan Cao, Lan Lei, Wenyuan Xu, Yujie Guo, Yikang He

Abstract readReview
In one paragraph

Review in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xianghu Zhao *College of Sports Medicine, Wuhan Sports University, Wuhan, 430079, Hubei Province, China.
Xiaohan Cao *School of Special Education and Rehabilitation, Binzhou Medical University, Yantai, 264000, Shandong Province, China.
Lan Lei *Department of Rehabilitation Medicine, Nanjing Pukou District Hospital of Traditional Chinese Medicine, Nanjing, 210000, Jiangsu Province, China.
Wenyuan XuGraduate School, Anhui University of Chinese Medicine, Heifei, 230000, Anhui Province, China.
Yujie GuoGraduate School, Anhui University of Chinese Medicine, Heifei, 230000, Anhui Province, China.
Yikang HeDepartment of Rehabilitation Medicine, Children's Hospital of Nanjing Medical University, Nanjing, 210008, Jiangsu Province, China. hantanger162@126.com.

Funding

Jiangsu Provincial Key R&D Programme No. BE2023023-1
6 · The paper itself

Abstract

backgroundFerroptosis, an emerging form of cell death, holds substantial promise for elucidating the etiology and improving treatment methods for cardiovascular diseases (CVDs). This work aims to comprehensively analyze cutting-edge research and future trends in CVDs, guiding research progress and the development of new therapies.

methodsWe retrieved articles and reviews related to ferroptosis in CVDs from the Web of Science Core Collection database, spanning the period from January 1, 2016, to April 22, 2025. Visualization and statistical analysis were performed using CiteSpace (6.2.R3) and VOSviewer (1.6.19) software.

resultsThe bibliometric analysis of ferroptosis in CVDs reveals a significant increase in research output since 2016, with a peak in publications in 2024. China leads in publication volume, with Southern Medical University being a key contributor. The International Journal of Molecular Sciences is the most prolific journal, and authors like Zhang Jing have the highest publication counts. Research focus has shifted over time, with recent emphasis on "cardiovascular diseases," "myocardial infarction," "lipid metabolism," "autophagy," and "mitochondrial dysfunction."

conclusionsOur bibliometric analysis reveals the rapid growth and evolving focus of ferroptosis research in CVDs, with China and the USA leading in output. Future work should prioritize developing biomarkers, multi-omics analyses, and the elucidation of specific molecular mechanisms to enhance clinical translation. Global collaboration remains key to accelerating innovation in this field.

Indexed as

BibliometricsBiomedical ResearchCardiovascular DiseasesFerroptosisAnimalsHumansBibliometric analysisCardiovascular diseasesCitespaceFerroptosisVisual analysisVosviewer

Identifiers

PMID41469923
PMCPMC12860062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.