Evidence map›Paper›PMID 41469883›Full record

SynthesisBiomedical engineering online2025

Outcomes of dental autotransplantation in relation to dental root formation. Systematic review and meta-analysis.

Hugo George Rowland, Marcela Ferrer Molina, Tawfiq Hijazi Alsadi, Susana Muwaquet Rodriguez

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Dental Traumatology in Contemporary Practice: From Evidence to Education and Clinical Practice.Dental traumatology : official publication of International Association for Dental Traumatology · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hugo George Rowland5th year student of the Dentistry degree of the Catholic University of Valencia, Valencia, Spain.
Marcela Ferrer MolinaDDS, PHD Department of Orthodontics, Faculty of Medicine and Health Science, Catholic University of Valencia, 46001, Valencia, Spain.
Tawfiq Hijazi AlsadiDDS, PHD Department of Orthodontics, Faculty of Medicine and Health Science, Catholic University of Valencia, 46001, Valencia, Spain.
Susana Muwaquet RodriguezDDS, PHD Department of Restorative dentistry and Endodontics, Faculty of Medicine and Health Sciences, Catholic University of Valencia (UCV), C/ Quevedo,2, 46001, Valencia, Spain. Susana.muwaquet@ucv.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDental autotransplantation (DAT) is a surgical procedure used to replace hopeless or missing teeth. The technique entails the purposeful extraction of a desired sound tooth, which is then implanted into another alveolar site of the same oral cavity.

objectivesTo analyse the survival rates and success rates of DAT in relation to donor teeth with an incomplete root development (open apex) and complete root formation (closed apex). Additionally, it attempts to evaluate the prognostic components of DAT with infection-related (inflammatory) root resorption, ankylosis, and pulpal necrosis complications. MATERIALS AND

methodsAn electronic search was conducted using EBSCO MEDLINE Web of Science, Scopus and Cochrane databases from January 2014 until November 2024. The selected articles were chosen within the parameters outlined in the Materials and Statistical Methodology section. The addressed PICO question "does the stage of the donor tooth's root development affect the long-standing prognosis and clinical outcomes of dental autotransplantation?".

resultsThe final 26 articles featured a total of 2837 transplanted teeth: 2192 donor teeth with an open apex and 645 donor teeth with a closed apex. The overall survival rate was 93.8% in the open apex group and 92.6% in the closed apex group. Success rate was 84.0% in the open apex group and 86.7% in the closed apex group. The rate of infection-related root resorption was 6.3% in the open apex group and 5.9% in the closed apex group. The rate of ankylosis was 4.4% in the open apex group and 6.7% in the closed apex group. The rate of pulp necrosis was 6.4% in the open apex group. No factors were identified as influencing the rate of pulp necrosis; however, the duration of follow-up was significantly associated with the rate (p = 0.057). None of the selected articles reported pulp necrosis rate in the closed apex; thus, no meta-analysis was possible.

conclusionDAT is a reliable treatment alternative for the replacement of lost teeth. The procedure yields low complication rates of infection-related root resorption, ankylosis, and pulp necrosis, while achieving high rates of survival and success. It can be accomplished with donor teeth that have an open or closed apex.

Indexed as

ToothTooth RootHumansTransplantation, AutologousTreatment OutcomeClosed apexComplete root formationDental autotransplantationIncomplete root formationOpen apexPrognosis factorsSuccess rateSurvival rate

Identifiers

PMID41469883
PMCPMC12755019

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.