Evidence map›Paper›PMID 41469800›Full record

ArticleNPJ digital medicine2025

GLANCE: continuous global-local exchange with consensus fusion for robust nodule segmentation.

Ruijie Ming, Fengpin Wang, Taotao Zheng, Zhongjian Yu, Xiaoping Huang, Shuangyan Huang, Han Tian, Wei Wang, Jinhai Deng, Huawen Liu and 1 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ruijie Ming *Department of Oncology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, China.
Fengpin Wang *Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Taotao Zheng *Department of Oncology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, China.
Zhongjian YuGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Xiaoping HuangDepartment of Oncology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, China.
Shuangyan HuangDepartment of Oncology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, China.
Han TianGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Wei WangDepartment of Oncology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, China.
Jinhai DengRichard Dimbleby Department of Cancer Research, Comprehensive Cancer Centre, Kings College London, London, UK. jinhaideng_kcl@163.com.
Huawen LiuDepartment of Oncology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, China. liuhuawen@cqu.edu.cn.
Yanfang ZhengGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China. zheng2020@gzhmu.edu.cn.

Funding

Chongqing medical scientific research project NO.2025MSXM125Chongqing University Central University Medical Integra- tion Project NO.2023CDJYGRH-ZD04National Natural Science Foundation of China No. 81974434the Affiliated Cancer Hospital & Institute of Guangzhou Medical Uni- versity No. 2020-YZ-01the Clinical Research Special Funding Fund of WU JIEPING MEDICAL FOUNDA- TION No. 320.6750.2022-22-38the Joint project of Chongqing Wanzhou Health Commission and Science and Technology Bureau NO.wzwjw-kw2024026the Science and Technology Program of Guangzhou City No. 202201020097Wu Jieping Medical Foundation No. 320.6750.2023-19-9
6 · The paper itself

Abstract

Accurate segmentation and detection of pulmonary nodules from computed tomography (CT) scans are critical for early lung cancer diagnosis but are hindered by the high diversity of nodule characteristics and the limitations of existing deep learning models. Conventional convolutional neural networks struggle with long-range context, while Transformers can neglect fine local details. We present GLANCE (Continuous Global-Local Exchange with Consensus Fusion), a novel dual-stream architecture designed to overcome these limitations. GLANCE features two parallel, co-evolving branches: a global context transformer to model long-range dependencies and a multi-receptive grouped atrous mixer to capture fine-grained local details. The core innovation is the cross-scale consensus fusion mechanism, which continuously integrates these complementary feature streams at every hierarchical scale, preventing representational clashes and promoting synergistic learning. A dual-head pyramid refinement decoder leverages these fused features to perform simultaneous nodule segmentation and center heatmap detection. Validated on four public benchmarks (LIDC-IDRI, LNDb, LUNA16, and Tianchi), GLANCE establishes a new state-of-the-art in both segmentation and detection. An extensive ablation study confirms that each architectural component, particularly the continuous fusion strategy, is critical to its superior performance.

Identifiers

PMID41469800
PMCPMC12827329

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