Evidence map›Paper›PMID 41469743›Full record

ArticleTropical medicine and health2025

Larvicidal effects of selected medicinal plant extracts against Anopheles arabiensis, Anopheles stephensi, and Aedes aegypti.

Negesse Gebissa, Ketema Tolossa, Araya Gebresilassie, Esayas Aklilu, Daniel Bisrat, Bersissa Kumsa, Sisay Dugassa

Abstract read
In one paragraph

Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Negesse GebissaAklilu Lemma Institute of Health Research, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia. negesse1973@gmail.com.
Ketema TolossaAklilu Lemma Institute of Health Research, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
Araya GebresilassieDepartment of Zoological Sciences, College of Natural and Computational Sciences, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
Esayas AkliluAklilu Lemma Institute of Health Research, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
Daniel BisratCollege of Health Science, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
Bersissa KumsaCollege of Veterinary Medicine and Agriculture, Addis Ababa University, PO Box 1176, Bishoftu, Ethiopia.
Sisay DugassaAklilu Lemma Institute of Health Research, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia. sisaydlw2@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence of resistance to synthetic (chemical) insecticides along with their harmful effects on human health, non-target organisms and the environment necessitates the development of new complementary bioinsecticides that are effective, environmentally friendly, biodegradable and target-specific. This study was undertaken to evaluate larvicidal activities of 80% methanol and n-hexane extracts of four plants that are traditionally used by communities against mosquitoes.

methodsThe dried plant parts of Ocimum lamiifolium, Amaranthus hybridus, Premna schimperi, and Lepidium sativum were extracted with 80% methanol and n-hexane solvents. Bioinsecticidal activities of these extracts were evaluated under laboratory condition in the range of 62.5-2000 ppm against late 3rd to early 4th instar larvae of An. arabiensis, An. stephensi and Ae. aegypti mosquitoes. Larval mortality was observed after 24 h of exposure. The mortality data were subjected to probit analysis to determine LC

resultsIn the concentration ranges of 62.5-2000 ppm, the LC

conclusionsThe n-hexane crude extracts of the tested plants have the potential to be used as bioinsecticides against larvae of An. arabiensis, An. stephensi and Ae. aegypti. Therefore, it is necessary to undertake studies that focus on bioassay-guided isolation, purification and structural elucidation of active compound (s) from the most active n-hexane fractions of the tested plants to develop a product that may complement the current existing vector control tools.

Indexed as

Arboviral diseasesBioinsecticidesLarvaeMalariaMedicinal plantsMosquitoes

Identifiers

PMID41469743
PMCPMC12754982

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.