Evidence map›Paper›PMID 41469722›Full record

ArticleJournal of ovarian research2025

Clinical outcomes of natural cycle IVF/M with the different sizes of dominant follicle at the time of hCG triggering.

Jianhua Li, Jing Chen, Tingting Jiao, Qingchen Cui, Jianye Wang, Yanbin Cheng, Ye Wang, Ye Xu, Ri-Cheng Chian, Youzhu Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jianhua Li *Department of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China.
Jing Chen *Department of Reproductive Medicine, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Tingting JiaoDepartment of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China.
Qingchen CuiSchool of Public Health, Xiamen University, Xiamen, 361102, China.
Jianye WangDepartment of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China.
Yanbin ChengDepartment of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China.
Ye WangDepartment of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China.
Ye XuDepartment of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China.
Ri-Cheng ChianCenter for Reproductive Medicine, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, P. R. of China. rchian@126.com.
Youzhu LiDepartment of Reproductive Medicine, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. liyouzhu2006@sina.com.
Shuang TianDepartment of Obstetrics and Gynecology, Reproductive Medical Center, Seventh Medical Center of PLA General Hospital, Beijing, 100700, China. tstiansh@qq.com.

Funding

Fujian Provincial Department of Science and Technology, Youth Innovation Program of the Natural Science Foundation 2023J05276Xiamen Science and Technology Bureau, Joint Project of Xiamen Natural Science Foundation 3502Z20227342
6 · The paper itself

Abstract

purposeThere is infertility treatment named natural cycle in vitro fertilization (IVF) combined with in vitro maturation (IVM) of immature oocytes (natural IVF/M). The objective of this study is to investigate the clinical outcomes of hCG triggering at the different sizes of dominant follicle during the treatment.

methodsA total of 705 patients with 1,011 natural IVF/M treatment cycles were included in this study. Among these 64 patients had repeated cycles, while 641 patients had only a single cycle. The cycles were divided into 4 groups according to the size of dominant follicle on the day of hCG injection (Group1:≤11.9 mm; Group2:12.0–13.9 mm༛Group3:14.0–15.9 mm༛Group4:≥16.0 mm).Through multivariate logistic regression analysis, candidate factors of number of mature oocytes, available and good quality embryos as well as clinical pregnancy rates were explored.

resultsOocytes maturation, fertilization, cleavage, available and good quality embryo rates (p > 0.05) were no difference among 4 groups. The rates for implantation, clinical pregnancy, miscarriage, premature delivery, and live birth were similar among the groups.

conclusionThe presence and different sizes of the dominant follicle in the ovaries during natural cycle IVF/M does not affect clinical outcomes.

Indexed as

Chorionic GonadotropinFertilization in VitroOvarian FollicleAdultFemaleHumansIn Vitro Oocyte Maturation TechniquesOocytesOvulation InductionPregnancyPregnancy RateTreatment OutcomeChorionic GonadotropinClinical outcomeIn vitro fertilizationIn vitro maturationNatural cycleSize of dominant follicle

Identifiers

PMID41469722
PMCPMC12860154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.