Evidence map›Paper›PMID 41469717›Full record

Observational studyWorld journal of surgical oncology2025

The effects of emotional distress on the postoperative survival and progression in patients with breast cancer: a prospective observational study.

Shanqing Xu, Li Yang, Juan Zhang, Aihua Tan, Dabao Xu, Jianbin Tong

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shanqing XuHunan Province Key Laboratory of Brain Homeostasis, Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P.R. China.
Li YangHunan Province Key Laboratory of Brain Homeostasis, Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P.R. China.
Juan ZhangDepartment of Breast Surgery, Tangshan People's Hospital, Tangshan, Hebei, China.
Aihua TanHunan Province Key Laboratory of Brain Homeostasis, Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P.R. China.
Dabao XuThird Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P.R. China. forxudabao@126.com.
Jianbin TongHunan Province Key Laboratory of Brain Homeostasis, Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P.R. China. jianbintong@csu.edu.cn.

Funding

National Natural Science Foundation of China N0. 82401427National Natural Science Foundation of China N0. 82571406
6 · The paper itself

Abstract

backgroundEmotional distress (ED), characterized by symptoms of depression and anxiety, is highly prevalent in patients with breast cancer. Although retrospective studies suggest an association between ED and adverse cancer outcomes, findings from prospective studies remain inconsistent.

objectiveThis prospective observational study aimed to investigate the association between emotional distress and long-term survival outcomes in patients with breast cancer following curative surgery.

methodsA total of 159 patients with breast cancer were enrolled. Baseline levels of emotional distress were assessed using standardized scales. Patients were prospectively followed for up to 7 years to monitor overall survival (OS) and progression-free survival (PFS). Inverse probability of treatment weighting (IPTW) was employed to adjust the baseline confounders.

resultsThe unadjusted 7-year OS and PFS rates in patients with ED were numerically lower than those without ED (OS: 78.5% vs. 93.7%; PFS: 76.9% vs. 89.3%). After adjustment using IPTW, emotional distress was independently associated with lower OS (adjusted HR = 6.52, 95% CI: 1.78-23.89, P = 0.005) and PFS (adjusted HR = 3.73, 95% CI: 1.19-11.71, P = 0.024).

conclusionThis study provides prospective evidence that emotional distress is associated with reduced survival and an increased risk of disease progression in breast cancer patients following curative surgery. These findings highlight the importance of integrating psychological assessment and supportive care into routine oncologic management.

Indexed as

Breast NeoplasmsMastectomyPsychological DistressAdultAgedDisease ProgressionFemaleFollow-Up StudiesHumansMiddle AgedPrognosisProspective StudiesSurvival RateAnxietyBreast cancerDepressionEmotional distressPrognosis

Identifiers

PMID41469717
PMCPMC12809896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.