Evidence map›Paper›PMID 41469675›Full record

ArticleBMC veterinary research2025

Epidemiology of BVD and persistently infected cattle across urban and peri-urban dairy farms in central, northern, and southern parts of Ethiopia.

Asamenew Tesfaye Melkamsew, Tesfaye Sisay Tessema, Abebe Garoma, Jan Paeshuyse

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Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Asamenew Tesfaye MelkamsewLaboratory of Host-Pathogen Interaction in Livestock, Department of Biosystems, Division of Animal and Human Health Engineering, KU Leuven University, Leuven, 3000, Belgium. asamenewtesfaye.melkamsew@kuleuven.be.
Tesfaye Sisay TessemaFaculty of Science, Institute of Biotechnology, Unit of Health Biotechnology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.
Abebe GaromaAnimal Health Institute, Units of Immunology, P.O. Box 04, Sebeta, Ethiopia.
Jan PaeshuyseLaboratory of Host-Pathogen Interaction in Livestock, Department of Biosystems, Division of Animal and Human Health Engineering, KU Leuven University, Leuven, 3000, Belgium. jan.paeshuyse@kuleuven.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBovine viral diarrhea (BVD) is an economically significant disease affecting both domestic and wild ruminant species. The causative agent is bovine viral diarrhea virus (BVDV) of the genus Pestivirus within the family Flaviviridae. In Ethiopia, information on the disease to initiate prevention and control measures is scarce. Hence, this study aimed to assess the prevalence of BVD and persistently infected cattle and identify the associated risk factors in dairy farms situated in urban and peri-urban areas. METHODOLOGY: An Enzyme-Linked Immunosorbent Assay (ELISA) technique was used to test serum samples collected from 1634 dairy cattle in 180 herds. Univariate analysis was conducted to assess the association between independent and outcome variables, and those with a significant association with the outcome variables were considered for a multivariable binary logistic regression model to identify potential risk factors.

resultsThe study revealed an overall antibody and antigen prevalence of 28.4% (95% confidence interval (CI): 26.2-30.6%) and 1.5% (95% confidence interval: 1.04-2.3%), respectively. The true within- and between-herd- sero-prevalence of BVD was 49.1% and 67.8%, respectively. The study also revealed a 0.94% (95% confidence interval (CI): 0.53-1.77) animal level and 6.4% (95% CI: 0.53-10.9) herd level prevalence of persistently infected animals. The study location, body condition score (BCS), diarrhea, herd size, origin of animals, and calf congenital anomalies were significantly associated with the prevalence of BVD (P < 0.05). Location, BCS, herd size, and origin of the animals were identified as potential risk factors (p < 0.05).

conclusionsOur study revealed that BVD is well established in commercial dairy farms, suggesting the need to design strong prevention and control measures. Future studies should be encouraged to determine the genetic diversity of the viruses in the country.

Indexed as

Bovine Virus Diarrhea-Mucosal DiseasePersistent InfectionAnimalsAntibodies, ViralCattleDairyingDiarrhea Viruses, Bovine ViralEnzyme-Linked Immunosorbent AssayEthiopiaFemalePrevalenceRisk FactorsSeroepidemiologic StudiesAntibodies, ViralBovine viral diarrhea virusBVDDairy cattleEthiopiaPIsPrevalenceRisk factors

Identifiers

PMID41469675
PMCPMC12882443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.