ArticleBMC public health2025
Facilitators and barriers to enhancing cognitive reserve in adults aged ≥ 50 years with HIV-associated mild neurocognitive disorder: a qualitative study.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Cognitive and fine motor performance in people above 65 years of age with and without HIV.Scientific reports · 2026Article
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9 authors.
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Abstract
backgroundPeople living with HIV (PLWH) aged ≥ 50 years face health challenges, including HIV-associated mild neurocognitive disorder. Cognitive reserve is a crucial neuroprotective mechanism that may help this population benefit from interventions designed to enhance cognitive function. However, the factors influencing cognitive reserve development in this group remain underexplored.
objectiveThis study aimed to identify facilitators and barriers to enhancing cognitive reserve in individuals aged ≥ 50 with HIV-associated mild neurocognitive disorder, to inform the development of personalized interventions.
methodsPurposive sampling was used to recruit participants from Luzhou, Sichuan. Semi-structured interviews were conducted with 26 PLWH aged ≥ 50 experiencing mild cognitive issues, including 19 men and seven women, with a mean age of 61.1 years. Interviews were recorded, transcribed, and analyzed using NVivo 14 and traditional content analysis.
resultsQualitative analysis identified two primary themes, comprising 12 sub-themes, related to facilitators and barriers to improving cognitive reserve. Key facilitators included perceived cognitive symptoms, compensatory strategies, individualized needs, valued self-efficacy, and external monitoring. Significant barriers included negative perceptions of health status, limited risk perception, concerns about privacy breaches, knowledge deficits, physical limitations, competing priorities, and financial cost.
conclusionThis study highlights key factors influencing cognitive reserve enhancement in PLWH aged ≥ 50 years, emphasizing the need for tailored interventions to address barriers and leverage facilitators. These findings provide a foundation for targeted programs to improve cognitive function in this population.
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