Evidence map›Paper›PMID 41469619›Full record

ArticleBMC public health2025

Post-Covid-19 symptoms, subjective work ability and sick leave 2 years after acute infection-results from a population-based long COVID study.

Stefanie Braig, Raphael S Peter, Alexandra Nieters, Hans-Georg Kräusslich, Stefan O Brockmann, Siri Göpel, Uta Merle, Jürgen M Steinacker, Winfried V Kern, Dietrich Rothenbacher and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stefanie Braig *Institute of Epidemiology and Medical Biometry, Ulm University, Helmholtzstraße 22, 89081, Ulm, Germany. stefanie.braig@uni-ulm.de.
Raphael S Peter *Institute of Epidemiology and Medical Biometry, Ulm University, Helmholtzstraße 22, 89081, Ulm, Germany.
Alexandra NietersInstitute for Immunodeficiency, Medical Centre and Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany.
Hans-Georg KräusslichDepartment of Infectious Diseases, Virology, Heidelberg University, Heidelberg, Germany.
Stefan O BrockmannDepartment of Health Protection, Infection Control and Epidemiology, Ministry of Social Affairs, Health and Integration, Baden-Wuerttemberg Federal State Health Office, Stuttgart, Germany.
Siri GöpelDepartment of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.
Uta MerleDepartment of Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany.
Jürgen M SteinackerDivision of Sports and Rehabilitation Medicine, Department of Medicine, Ulm University Hospital, Ulm, Germany.
Winfried V Kern *Division of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany.
Dietrich Rothenbacher *Institute of Epidemiology and Medical Biometry, Ulm University, Helmholtzstraße 22, 89081, Ulm, Germany.
EPILOC Phase 3a Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe post-COVID syndrome (PCS) is associated with reduced work ability, increased sick leave and delayed return to work. Yet, the relationship is complex due to a heterogeneous set of PCS symptoms and the multifaceted nature of work ability.

methodsBased on a population-based longitudinal study (n = 5422, 18-65 years) conducted in the Southwest of Germany, we describe the evolution of work ability (mWAI1), task-related work ability (mWAI2), and sick leave 6-12 and 24 months after a SARS-CoV-2 index infection and confirmed by Polymerase Chain Reaction. Descriptive analyses on mWAI1 and mWAI2 and adjusted linear regression analyses were performed.

results1.1% of our population was continuously on sick leave since the initial SARS-CoV-2 infection (about 24 months after the infection). Pre-infection mWAI1 was not regained due to persisting or newly occurring symptoms of fatigue, neurocognitive impairment and anxiety/depression/sleep disorders that were related also to lower mWAI2. Effect modifiers of the associations between risk factors and mWAI1 or mWAI2 were age, working tasks, and comorbid mental conditions. Further SARS-CoV-2 infections were associated with poorer mWAI2 in physically (regression coefficient, 95% confidence intervals: -3.45 (-6.15,-0.74) but not mentally working participants (0.20 (-0.54,0.95)) and age proved to be a stronger risk factor for mWAI2 in physically working subjects.

conclusionsWe confirmed known risk factors but further emphasized effect modifiers like working task or comorbid mental disorders for work ability and described variables related to sick leave after SARS-CoV-2 infection.

Indexed as

COVID-19Sick LeaveWork Capacity EvaluationAdolescentAdultAgedFemaleGermanyHumansLongitudinal StudiesMaleMiddle AgedPost-Acute COVID-19 SyndromeReturn to WorkRisk FactorsSARS-CoV-2Post-COVID syndromeSARS-CoV-2WAIWork abilityWorking task

Identifiers

PMID41469619
PMCPMC12849167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.