Evidence map›Paper›PMID 41469597›Full record

ArticleBMC public health2025

Gender, mental health symptoms, loss to clinic, and viral non-suppression 6 months after HIV care initiation among a cohort of people with HIV in Cameroon.

Angela M Parcesepe, Lindsey M Filiatreau, Peter Vanes Ebasone, Anastase Dzudie, Marcel Yotebieng, Kathryn Anastos, Eric Pefura-Yone, Annereke Nyenti, Denis Nash

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angela M ParcesepeDepartment of Maternal and Child Health, University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, NC, USA. angela_parcesepe@unc.edu.
Lindsey M FiliatreauWashington University in St. Louis, St. Louis, MO, USA.
Peter Vanes EbasoneClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Anastase DzudieClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Marcel YotebiengDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Kathryn AnastosDepartments of Medicine and Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Eric Pefura-YoneJamot Hospital, Yaounde, Cameroon.
Annereke NyentiLimbe Regional Hospital, Limbe, Cameroon.
Denis NashCity University of New York, Institute of Implementation Science in Population Health, Graduate School of Public Health and Health Policy, New York, NY, USA.

Funding

"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
Understanding and addressing mental and substance use disorders among people living with HIV in low-resource settingsK01MH114721 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARCESEPE, ANGELA · 2018 to 2022
$766k
Designing adaptive implementation strategies for mental health care in persons living with HIV in South Africa (DASH-SA)K01MH136924 · NIMH · WASHINGTON UNIVERSITY · PI Lindsey Filiatreau · 2024 to 2026
$537k
National Institute of Allergy and Infectious Diseases U01AI096299NIAID NIH HHS U01 AI096299NIMH NIH HHS K01 MH114721NIMH NIH HHS K01MH114721NIMH NIH HHS K01 MH136924
6 · The paper itself

Abstract

backgroundPeople with HIV (PWH) experience high levels of mental health or substance use disorders (MSDs) which may compromise HIV treatment outcomes. Differences in the relationship between MSDs and HIV treatment outcomes by gender remain understudied.

methodsWe conducted interviews with 426 PWH aged ≥ 21 years initiating HIV care in Cameroon between June 2019 and March 2020. Clinic data and laboratory results were used to ascertain loss to clinic and viral non-suppression six months after HIV care initiation. We used log binomial regression models to assess the relationship between symptoms of depression (PHQ-9 scores > 9), anxiety (GAD-7 scores > 9), post-traumatic stress disorder (PTSD; PCL-5 scores > 30), and harmful alcohol use (AUDIT scores > 15) at HIV care initiation and 6-month loss to clinic and viral non-suppression in the study population overall, and among men and women, separately.

resultsNearly 25% of individuals (N = 100) were lost to clinic at 6 months. Among the 326 individuals retained in care at their original clinic at 6 months, 234 had a measured viral load, of whom 28% were virally non-suppressed (N = 65). Among men, the risk of disengagement was greater among those who reported PTSD symptoms at care initiation compared to those who did not. Viral non-suppression was significantly higher among those reporting symptoms of anxiety at care initiation in the population retained overall and among men.

conclusionsMen initiating HIV care with poor mental health may be particularly vulnerable to unstable care engagement and viral non-suppression. Interventions are needed for men specifically to foster improved mental health.

Indexed as

HIV InfectionsMental HealthAdultAnxietyCameroonCohort StudiesDepressionFemaleHumansMaleMiddle AgedSex FactorsStress Disorders, Post-TraumaticViral LoadYoung AdultAfricaAnxietyCameroonDepressionGenderHIV

Identifiers

PMID41469597
PMCPMC12754916

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.