ArticleJournal of Korean medical science2025
Comparative Study of the Clinical Characteristics of Patients With Sexually Transmitted Infections Diagnosed by Nucleic Acid Amplification Tests.
Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Epidemiology of Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, and Ureaplasma urealyticum in males of andrology clinics in Nanjing, China: a 10 years retrospective study.Frontiers in cellular and infection microbiology · 2026Article
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5 authors.
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Abstract
backgroundSexually transmitted infections (STIs) caused by
methodsThis retrospective cohort study included adult, non-pregnant patients diagnosed with CT, MG, or NG via NAAT at a secondary care hospital between 2012 and 2024. Clinical characteristics were compared using the Kruskal-Wallis test, and multivariate logistic regression identified risk factors for NAAT clearance failure in patients with follow-up NAAT within three months.
resultsAmong 500 STI cases, 80.8% were female, with a median age of 27.0 years. CT was the most common pathogen (53.8%), followed by MG (37.2%) and NG (9.0%). CT infections had the highest complication rate (28.6%), while NG infections were more frequently symptomatic (77.8%) and associated with pyuria (46.4%). Of 221 patients with follow-up NAAT, 14.9% failed clearance. MG infection (adjusted odds ratio [aOR], 6.100; 95% confidence interval [CI], 2.711-13.725;
conclusionCT showed the highest complication rate and NG was the most symptomatic. MG was a key predictor of NAAT clearance failure, underscoring the need for antimicrobial resistance monitoring and optimized retreatment strategies.
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