ArticleJournal of Korean medical science2025
Clinical Outcomes of Robot-Assisted "Asleep" Deep Brain Stimulation With Microelectrode Recording in Parkinson's Disease.
Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- Robot-Assisted Deep Brain Stimulation for Parkinson's Disease : Accuracy, Workflow, Clinical Outcomes, and Safety.Journal of Korean Neurosurgical Society · 2026Article
- Accuracy and Outcomes of KYMERO Robot-Guided Deep Brain Stimulation for Dystonia : Retrospective Cohort Analysis.Journal of Korean Neurosurgical Society · 2026Article
- Microvascular Anastomoses and Beyond: Exploring the Role of Robotic Systems in Microneurosurgery.Journal of robotic surgery · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundDeep brain stimulation (DBS) is a well-established treatment for movement disorders, particularly Parkinson's disease (PD), where precise electrode placement is critical for optimal outcomes. With advances in robotic systems and imaging technologies, robot-assisted asleep DBS combined with microelectrode recording (MER) has emerged as a promising technique. This study aimed to evaluate the surgical accuracy and clinical outcomes of robot-assisted asleep DBS with MER in PD patients.
methodsWe conducted a retrospective review of PD patients who underwent either robot-assisted asleep DBS or conventional manual frame-based DBS at a single center between August 2021 and August 2024. Targeting accuracy was assessed using radial error measured on intraoperative computed tomography. Clinical outcomes were evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS), levodopa equivalent daily dose (LEDD), and the Parkinson's Disease Questionnaire-39 (PDQ-39) at baseline, 6 months, and 1 year postoperatively.
resultsA total of 51 patients underwent robot-assisted asleep DBS. This group demonstrated significantly higher targeting accuracy than the manual frame-based group (
conclusionRobot-assisted asleep DBS significantly improves targeting accuracy while maintaining comparable clinical outcomes to manual frame-based DBS. Asleep DBS with MER is a safe and effective approach, enhancing patient comfort without compromising efficacy. These findings support the broader adoption of robotic techniques in DBS for PD.
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Registered trials
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