Evidence map›Paper›PMID 41468882›Full record

ArticleACS applied materials & interfaces2026

Enhancing Bone Healing Using Carvacrol on Calcium Phosphate Substrates.

Susmita Bose, Aditi Dahiya, Yongdeok Jo, Ujjayan Majumdar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susmita BoseW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0001-8601-016X
Aditi DahiyaW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0001-5009-3952
Yongdeok JoW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0002-1136-1245
Ujjayan MajumdarW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.

Funding

3D Printed Calcium Phosphate Scaffolds with Natural Medicinal Compounds for Dental ApplicationsR01DE029204 · NIDCR · WASHINGTON STATE UNIVERSITY · PI BOSE, SUSMITA · 2020 to 2024
$1.7M
Surface Modified Metal Implant Using doped HydroxyapatiteR56AR066361 · NIAMS · WASHINGTON STATE UNIVERSITY · PI BOSE, SUSMITA · 2022 to 2024
$638k
NIAMS NIH HHS R56 AR066361NIDCR NIH HHS R01 DE029204
6 · The paper itself

Abstract

Carvacrol has therapeutic potential due to its anti-inflammatory, antioxidant, and antimicrobial properties. Here, Carvacrol was incorporated on three-dimensionally printed tricalcium phosphate (3DP TCP), hydroxyapatite-pressed (HAP) discs, and plasma-sprayed HA-coated Ti6Al4V (HA-Ti64) implants to evaluate its localized release and impact on bone regeneration. Carvacrol release from HA-Ti64 reaches a ∼100% within 3 days in acidic pH, whereas from HAP discs, it releases 60% over 14 days.

Indexed as

Bone RegenerationCalcium PhosphatesCymenesAlloysAnimalsDurapatiteHumansMesenchymal Stem CellsOsteoblastsOsteoclastsOsteogenesisRatsTHP-1 CellsTitaniumAlloyscalcium phosphateCalcium PhosphatescarvacrolCymenesDurapatiteTitaniumtitanium alloy (TiAl6V4)tricalcium phosphate3D printingbone tissue engineeringcarvacrolin vivo rat distal femurplasma coating

Identifiers

PMID41468882
PMCPMC13182689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.