Evidence map›Paper›PMID 41468665›Full record

ArticleJournal of inorganic biochemistry2026

Structural and mechanistic insights into the sulfur transfer protein SufU from Staphylococcus aureus.

Emily Sabo, Connor Nelson, Delanie Huntoon, Jing Yang, Martin Kirk, Simon J George, Brian Bennett, Jeffrey M Boyd, Richard C Holz

Abstract read
In one paragraph

Article in Journal of inorganic biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emily SaboDepartment of Chemistry, Colorado School of Mines, Golden, CO 80401, United States of America.
Connor NelsonDepartment of Chemistry, Colorado School of Mines, Golden, CO 80401, United States of America.
Delanie HuntoonDepartment of Physics, 540 N. 15th St., Marquette University, Milwaukee, WI 53233, United States of America.
Jing YangDepartment of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, NM 87131, United States of America.
Martin KirkDepartment of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, NM 87131, United States of America.
Simon J GeorgeSimon Scientific, P.O. Box 71024, Richmond, CA 94807, United States of America; SETI Institute, 339 Bernardo Ave Suite 200, Mountain View, CA 94043, United States of America.
Brian BennettDepartment of Physics, 540 N. 15th St., Marquette University, Milwaukee, WI 53233, United States of America.
Jeffrey M BoydDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901, United States of America.
Richard C HolzDepartment of Chemistry, Colorado School of Mines, Golden, CO 80401, United States of America. Electronic address: rholz@mines.edu.

Funding

X-Ray Raman and Vibrational Mossbauer of MetalloproteinsR01GM065440 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CRAMER, STEPHEN P. · 2002 to 2025
$7.3M
Spectroscopic Studies of Molybdoenzymes & ModelsR01GM057378 · NIGMS · UNIVERSITY OF NEW MEXICO · PI MARTIN L KIRK · 1998 to 2026
$6.9M
First-in-class rationally designed inhibitors of the SUF-like pathway of iron-sulfur cluster biosynthesis for treating infections caused by S. aureus and other Gram-positive bacteriaR21AI176058 · NIAID · COLORADO SCHOOL OF MINES · PI HOLZ, RICHARD C · 2024 to 2025
$425k
NIAID NIH HHS R21 AI176058NIGMS NIH HHS R01 GM057378NIGMS NIH HHS R01 GM065440
6 · The paper itself

Abstract

Substitution of the active site Zn

Indexed as

Bacterial ProteinsCarrier ProteinsStaphylococcus aureusSulfurCatalytic DomainCobaltX-Ray Absorption SpectroscopyZincBacterial ProteinsCarrier ProteinsCobaltSulfurZincCobaltEPREXAFSFe-S cluster biosynthesisMetalloenzymePersulfideSufSulfurSulfur transferZinc

Identifiers

PMID41468665
PMCPMC13094537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.