Evidence map›Paper›PMID 41468150›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2026

Can Chlorhexidine Bathing Reduce Candidozyma auris Shedding?

Gabrielle M Gussin, Raveena D Singh, Ken Kleinman, Raheeb Saavedra, Julie A Shimabukuro, Evelyn A Flores, Loren G Miller, Cassiana E Bittencourt, Susan S Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Transfer ofOpen forum infectious diseases · 2026
    Article
  2. Article
  3. Frontiers in cellular and infection microbiology · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabrielle M GussinDivision of Infectious Diseases, University of California Irvine School of Medicine, Irvine, California, USA.ORCID 0000-0001-8051-7613
Raveena D SinghDivision of Infectious Diseases, University of California Irvine School of Medicine, Irvine, California, USA.
Ken KleinmanProgram in Biostatistics, University of Massachusetts Amherst School of Public Health and Health Sciences, Amherst, Massachusetts, USA.
Raheeb SaavedraDivision of Infectious Diseases, University of California Irvine School of Medicine, Irvine, California, USA.
Julie A ShimabukuroDepartment of Pathology and Laboratory Medicine, University of California Irvine Health, Orange, California, USA.
Evelyn A FloresDivision of Infectious Disease, Lundquist Institute at Harbor, University of California Los Angeles Medical Center, and Harbor-University of California Los Angeles Medical Center, Torrance, California, USA.
Loren G MillerDivision of Infectious Disease, Lundquist Institute at Harbor, University of California Los Angeles Medical Center, and Harbor-University of California Los Angeles Medical Center, Torrance, California, USA.ORCID 0000-0003-0487-1711
Cassiana E BittencourtProgram in Biostatistics, University of Massachusetts Amherst School of Public Health and Health Sciences, Amherst, Massachusetts, USA.
Susan S HuangDivision of Infectious Diseases, University of California Irvine School of Medicine, Irvine, California, USA.ORCID 0009-0002-1524-9004

Funding

Simulating the Spread and Control of Multiple MDROs Across a Network of Different Nursing HomesU19AI172725 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Bruce Y Lee · 2024 to 2026
$10.9M
Endemic and Emerging Multidrug Resistant Organisms in Nursing Homes: A Neglected Clinical SettingF31AI172386 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI GUSSIN, GABRIELLE · 2022 to 2024
$131k
NIAID NIH HHS F31 AI172386NIAID NIH HHS U19 AI172725
6 · The paper itself

Abstract

This settle plate study demonstrated rapid Candidozyma auris shedding during nursing home caregiving activities, with an 80% reduction when residual chlorhexidine gluconate concentrations ≥156 µg/mL. Findings highlight high-contact care as key transmission points and provide novel evidence that chlorhexidine-based decolonization can effectively mitigate C. auris transmission risk in long-term care.

Indexed as

Anti-Infective Agents, LocalBathsCandida aurisChlorhexidineHumansNursing HomesAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconateCandida aurischlorhexidine bathingdecolonizationnursing homes

Identifiers

PMID41468150
PMCPMC12952228

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.