Evidence map›Paper›PMID 41467970›Full record

ArticleEJNMMI physics2025

A hybrid curve-fitting method for radiation dosimetry evaluation and simultaneous multi-organ biodistribution assessment in total-body dynamic PET/CT: application to a novel PD-L1-targeted tracer.

Yunze Xie, Wenxin Tang, Lichao Zhang, Guobing Liu, Hongcheng Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunze Xie *Shanghai Institute of Medical Imaging, Shanghai, 200032, People's Republic of China.
Wenxin Tang *Shanghai Institute of Medical Imaging, Shanghai, 200032, People's Republic of China.
Lichao Zhang *Shanghai Institute of Medical Imaging, Shanghai, 200032, People's Republic of China.
Guobing LiuShanghai Institute of Medical Imaging, Shanghai, 200032, People's Republic of China. liu.guobing@zs-hospital.sh.cn.
Hongcheng ShiShanghai Institute of Medical Imaging, Shanghai, 200032, People's Republic of China. shi.hongcheng@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0001-7457-876X

Funding

Health and Family Planning Commissionof Sichuan Province 23SHS01200; 23SHS01200-01Key Laboratory of Dynamic Cognitive System of Electromagnetic Spectrum Space CEIEC-2022-ZM02-0219National Key Clinical Specialty Discipline Construction Program of China YWP2022-007the Shanghai 2024 "Explorer" program 24TS1411100
6 · The paper itself

Abstract

objectiveThis study explored a hybrid curve-fitting method optimized for radiation dosimetry evaluation in total-body dynamic positron emission tomography/computed tomography (PET/CT) imaging, compared to conventional methods reliant on multi-time-point static acquisition protocols, and evaluated the radiation dosimetry results and organ biodistribution of [

methodsA total of 16 patients with solid tumors underwent a 60-min dynamic PET acquisition immediately after administration of [

resultsThe [

conclusionThe radiation dosimetry results obtained from both the RM and the HM consistently support the safety and feasibility of total-body PET/CT imaging using [

Indexed as

Dynamic imagingInternal dosimetryPositron emission tomography (PET)Programmed death-ligand 1 (PDL-1)

Identifiers

PMID41467970
PMCPMC12864596

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.