Evidence map›Paper›PMID 41467811›Full record

ArticleMicrobiology spectrum2026

High-throughput single-cell isolation of

Lam Hai Ha, Yue Yuan On, Clarice Pohan, Jungwon Lee, Shaun Hong Chuen How, Yik-Ying Teo, Henning Seedorf, Jean-Sebastien Gounot, Niranjan Nagarajan

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lam Hai Ha *Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0009-0004-1551-7309
Yue Yuan On *Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0003-1823-8853
Clarice PohanGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0009-0003-4867-3036
Jungwon LeeGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0009-0007-1821-1876
Shaun Hong Chuen HowGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0009-0003-3859-5329
Yik-Ying TeoLife Sciences Institute, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-7522-0601
Henning SeedorfTemasek Lifesciences Laboratory, Singapore, Singapore.ORCID 0000-0002-5763-0236
Jean-Sebastien GounotGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0003-2368-8779
Niranjan NagarajanGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0003-0850-5604

Funding

National Medical Research Council CIRG22jul-0023National Research Foundation Singapore NRFI09-0015
6 · The paper itself

Abstract

IMPORTANCE: The field of high-throughput microbial culturomics is still in its early stages. Enhancing our ability to isolate and phenotypically test bacterial strains from complex communities is crucial for advancing microbiome research and healthcare development. Given the time and cost inefficiencies of traditional culturing methods, a more efficient, high-throughput approach to obtain isolates is needed. In the present study, we assessed a single-cell dispensing platform and developed a workflow to isolate diverse

Indexed as

BifidobacteriumGastrointestinal MicrobiomeSingle-Cell AnalysisFecesGenome, BacterialHumansPhylogenyWhole Genome SequencingBifidobacteriumculturomicshigh-throughput isolation

Identifiers

PMID41467811
PMCPMC12889045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.