Evidence map›Paper›PMID 41467803›Full record

ArticleAntimicrobial agents and chemotherapy2026

Phylogenetic diversification and fitness trade-offs of TetA variants in mediating eravacycline resistance in

Meimei Fan, Zhixun Zhang, Xiaowei Liu, Liqin Deng, Yijie Lei, Feng Chen, Yuanyuan Ying, Chengfeng Fan, Jiaxin Gao, Zheer Ren and 12 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Meimei Fan *Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Zhixun Zhang *Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Xiaowei LiuZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Liqin DengZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yijie LeiZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Feng ChenZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yuanyuan YingZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Chengfeng FanZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Jiaxin GaoZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Zheer RenZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Jiayi GuZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yuying XiaZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yifan YuanZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Keyu ZhangZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Junfei ZhuZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yilin YangZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Weining SunZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.ORCID 0000-0001-7857-2306
Kaiying ChengZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.ORCID 0000-0001-8613-6467
Alessandra CarattoliDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-6120-6526
Christoph M TangSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8366-3245
Zhen ShenDepartment of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.ORCID 0009-0006-1034-0705
Guangyu LiuZhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Biomedical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.ORCID 0000-0002-5865-431X

Funding

Hangzhou Youth Innovation Team Project TD2023020HZNU scientific research and innovation team project TD2025012National Natural Science Foundation of China 32300157National Natural Science Foundation of China 82272374Natural Science Foundation of Zhejiang Province LQ24C010002Scientific Research Project of the Zhejiang Provincial Education Department Y202351652Scientific Research Project of the Zhejiang Provincial Education Department Y202351700
6 · The paper itself

Abstract

The role of TetA variants in mediating tigecycline and eravacycline resistance in

Indexed as

Anti-Bacterial AgentsBacterial ProteinsKlebsiella pneumoniaeTetracyclinesCadmiumDrug Resistance, BacterialDrug Resistance, Multiple, BacterialHumansHydrogen PeroxideKlebsiella InfectionsMicrobial Sensitivity TestsPhylogenyTigecyclineAnti-Bacterial AgentsBacterial ProteinsCadmiumeravacyclineHydrogen PeroxideTetracyclinesTigecyclineadvanced tetracyclinesdisinfectantsecological trade-offfitness costsheavy metalsplasmids

Identifiers

PMID41467803
PMCPMC12888893

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.