Evidence map›Paper›PMID 41467588›Full record

ArticleTurkish journal of orthodontics2025

Evaluation of in Vivo Effects of Low-Intensity Pulsed Ultrasound and Low-Level Laser Therapy on Premaxillary Suture During Rapid Maxillary Expansion.

Esra Erkan, Şeniz Karaçay, Esra Çikler, İlayda Özge Polat

Abstract read
In one paragraph

Article in Turkish journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Esra ErkanPrivate Practice, İstanbul, Türkiye.ORCID 0000-0002-3259-5999
Şeniz KaraçayUniversity of Health Sciences Faculty of Dentistry, Department of Orthodontics, İstanbul, Türkiye.ORCID 0000-0002-1206-2546
Esra ÇiklerUniversity of Health Sciences Faculty of Medicine, Department of Histology and Embryology, İstanbul, Türkiye.ORCID 0000-0002-5756-5892
İlayda Özge PolatUniversity of Health Sciences Faculty of Medicine, Department of Histology and Embryology, İstanbul, Türkiye.ORCID 0000-0002-5904-9998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate and compare the effects of low-intensity pulsed ultrasound (LIPUS), low-level laser therapy (LLLT), and their combined effects on sutural bone regeneration during rapid maxillary expansion (RME) of rats. Methods: Twenty-eight Sprague-Dawley rats were randomly assigned to four groups: LLLT group, LIPUS group, combination group, and control group. RME was performed on all groups for 11 days. The Both LLLT and LIPUS groups received their respective therapies (30 J/cm Results: The number of osteoblasts was significantly higher in the combination group than in the control group (p<0.05). The combination group showed the highest general BMP-2 immunoreactivity and cellular VEGF immunoreactivity among all groups, and exhibited increased cellular OPN immunoreactivity compared with the control group (p<0.05). Both the area of newly formed bone (p<0.05) and suture width (p<0.01) were significantly greater in the LIPUS group than in the LLLT group. Conclusion: LIPUS is a more effective adjuvant therapy than LLLT for increasing sutural bone formation during RME. Combined therapy with LIPUS and LLLT has a synergistic effect and accelerates sutural bone regeneration by enhancing cellular activation more than either LIPUS or LLLT alone.

Indexed as

low-intensity pulsed ultrasoundLow-level laser therapymaxillary expansionrat

Identifiers

PMID41467588
PMCPMC12758436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.