Evidence map›Paper›PMID 41467577›Full record

ArticleThe British journal of surgery2025

Parallel Endografting And Chimney Endovascular (PEACE) registry outcomes in emergency repair of complex abdominal aortic aneurysms.

Angelos Karelis, Donald Adam, Michele Piazza, Giovanni Tinelli, Enrico Gallito, Miltiadis Matsagkas, Barend Mees, Kevin Mani, Mario D'Oria, Wassim Mansour and 5 more

Abstract readMulticenter Study
In one paragraph

Article in The British journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Angelos KarelisDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.ORCID 0000-0001-8971-658X
Donald AdamDepartment of Vascular Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Michele PiazzaDivision of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Padua University School of Medicine, Padua, Italy.
Giovanni TinelliUnit of Vascular Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-2212-3226
Enrico GallitoVascular Surgery, University of Bologna, DIMEC, Bologna, Italy.
Miltiadis MatsagkasDepartment of Vascular Surgery, Larissa University Hospital, Faculty of Medicine, University of Thessaly, Larissa, Greece.
Barend MeesDepartment of Vascular Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0001-6545-5813
Kevin ManiDivision of Vascular Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Mario D'OriaDivision of Vascular and Endovascular Surgery, Cardiovascular Department, University Hospital of Trieste, Trieste, Italy.ORCID 0000-0002-7156-7827
Wassim MansourDepartment of General Surgery and Surgical Specialties, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-7774-8178
Enrico CieriVascular and Endovascular Surgery Unit University of Perugia, Ospedale S. Maria Della Misericordia, Perugia, Italy.
Tilo KölbelGerman Aortic Centre Hamburg, Department of Vascular Medicine, University Heart and Vascular Center UKE Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Björn SonessonDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Nuno V DiasDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
PEACE Contributors

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChimney endovascular aneurysm repair (chEVAR) techniques have been described to manage a group of patients who are unsuitable for either open aortic aneurysm surgery or a variety of standard endovascular repair techniques. The aim of this study was to assess the long-term clinical outcomes of chEVAR in emergency settings for patients with abdominal aortic aneurysms that have complex morphology.

methodsThis was a multicentre retrospective study that included all consecutive patients undergoing urgent chEVAR with at least one chimney/parallel graft up to June 2021. Outcomes that were captured included 30-day mortality, long-term overall survival, aneurysm-related mortality, chimney-related complications, and target vessel patency.

resultsSome 118 patients (mean(s.d.) age of 77(8) years; 72.0% male) underwent urgent or emergency chEVAR, 78 (66.1%) due to aortic rupture. The mean(s.d.) number of chimneys used per patient was 1.6(0.7). Technical success was achieved in 90.6% of patients, with a 30-day mortality rate of 17.7%. The mean follow-up was 4(3) years. Estimated overall survival was 69 ± 5% at 3 years, 45 ± 6% at 5 years, and 32 ± 6% at 7 years. Freedom from aneurysm-related mortality was 58 ± 6% at 5 years and 53 ± 6% at 7 years. In patients surviving the perioperative 30-day interval, freedom from aneurysm-related mortality was 73 ± 6% at 5 years and 66 ± 7% at 7 years. Primary target vessel patency at 5 and 7 years was 87 ± 4%, with renal arteries most frequently affected. Late reinterventions occurred in 16.1% of patients, mostly for type Ia endoleaks (8 of 25 reinterventions (32%)) and type Ib endoleaks (5 of 25 reinterventions (20%)).

conclusionIn this Parallel Endografting And Chimney Endovascular (PEACE) registry study, chEVAR was associated with a high rate of technical success and acceptable early outcomes, but, in the longer term, was associated with high rates of reintervention and mortality. It appears to represent a reasonable alternative technique for patients presenting as an emergency with complex aortic aneurysm morphology when standard open and endovascular techniques are not feasible.

Indexed as

Aortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationEndovascular ProceduresAgedAged, 80 and overBlood Vessel ProsthesisEmergenciesFemaleHumansMalePostoperative ComplicationsRegistriesRetrospective StudiesTreatment Outcome

Identifiers

PMID41467577
PMCPMC12750328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.