Evidence map›Paper›PMID 41467455›Full record

Trial reportPM & R : the journal of injury, function, and rehabilitation2026

Feasibility randomized controlled trial of transcranial direct current stimulation (tDCS) to reduce falls in Parkinson's disease.

Jader Vinicius Silva Rocha, Marcela Barçante, Tiffany Holz Pereira, Juliana Cristina de Souza, Augusto Boening, Guilherme Peixoto Tinoco Areas, Lucas Rodrigues Nascimento, Fernando Zanela da Silva Areas

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PM & R : the journal of injury, function, and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jader Vinicius Silva RochaLaboratory of Neuromodulation and Neurorehabilitation, Universidade Federal do Espírito Santo, Vitória, Brazil.
Marcela BarçanteLaboratory of Neuromodulation and Neurorehabilitation, Universidade Federal do Espírito Santo, Vitória, Brazil.
Tiffany Holz PereiraLaboratory of Neuromodulation and Neurorehabilitation, Universidade Federal do Espírito Santo, Vitória, Brazil.
Juliana Cristina de SouzaLaboratory of Neuromodulation and Neurorehabilitation, Universidade Federal do Espírito Santo, Vitória, Brazil.
Augusto BoeningLaboratorio Caminhar, Universidade Federal do Espirito Santo, Vitória, Brazil.
Guilherme Peixoto Tinoco AreasPhysiology Science Laboratory, Universidade Federal do Amazonas, Manaus, Brazil.
Lucas Rodrigues NascimentoLaboratorio Caminhar, Universidade Federal do Espirito Santo, Vitória, Brazil.
Fernando Zanela da Silva AreasLaboratory of Neuromodulation and Neurorehabilitation, Universidade Federal do Espírito Santo, Vitória, Brazil.ORCID https://orcid.org/0000-0002-2068-2606

Funding

Fundação de Amparo à Pesquisa e Inovação do Espírito Santo
6 · The paper itself

Abstract

backgroundParkinson's disease (PD) significantly impairs mobility and increases the risk of falls.

objectiveTo evaluate the feasibility and safety of a randomized controlled trial protocol investigating the effects of transcranial direct current stimulation (tDCS) combined with gait training.

methodsTwenty-five individuals with PD were assessed for eligibility to participate in either active tDCS walking training (experimental group) or sham tDCS walking training (control group) for 4 weeks, consisting of 12 30-minute sessions.

resultsOf the 25 individuals assessed, 11 met the eligibility criteria (44%), and 9 were enrolled in the study (36% of eligible, 22.5% of total). Adherence to the intervention was high (88.9%), and no serious adverse events were reported.

conclusionThe protocol was found to be safe and feasible, though methodological adjustments, particularly in eligibility criteria and logistical procedures, are recommended to improve future implementation. These findings support the feasibility of conducting a full-scale randomized controlled trial to evaluate the combined effects of tDCS and gait training in individuals with PD.

Indexed as

Accidental FallsParkinson DiseaseTranscranial Direct Current StimulationAgedFeasibility StudiesFemaleGaitHumansMaleMiddle AgedPostural BalanceTreatment OutcomeWalking

Identifiers

PMID41467455
PMCPMC13358438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.