ArticleGigaScience2026
Charting immune variation through genetics and single-cell genomics.
Article in GigaScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral blood.Science advances · 2026Article
- Envisioning population-scale immune multi-omics atlas projects.Clinical and translational medicine · 2026Article
- Review
- Integrative single-cell transcriptomics and proteomics reveal an immunometabolic framework for MSC-exosome-mediated remodeling of expanded NK cells.GigaScience · 2026Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large-scale single-cell genomics projects have revolutionized our understanding of human immune variation. Yet most studies to date have been Eurocentric, limited in cell-type resolution, or restricted to a single data modality. The newly published Chinese Immune Multi-Omics Atlas helps address these gaps by profiling 428 healthy Chinese adults using a multiomics single-cell approach that combines single-cell RNA sequencing and single-cell chromatin accessibility sequencing across over 10 million immune cells. This integrated strategy enabled the identification of 73 distinct immune cell subsets and the construction of cell-type-specific gene regulatory networks linking noncoding enhancers to target genes. The atlas delineated hundreds of enhancer modules (eRegulons), highlighting both established and novel regulators of immune cell identity. By aligning transcriptomic and epigenomic maps, Yin et al. show how expanding both the ancestral diversity and data modalities of immune cell genomics can reveal new biology and provide a valuable addition to global reference cell atlases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.