Evidence map›Paper›PMID 41467366›Full record

GuidelineJournal of the American Heart Association2026

Pediatric Intracerebral Hemorrhage Management-Consensus Statement of the International Pediatric Stroke Organization-Part 1: Acute Phase and Workup.

Grégoire Boulouis, Christine K Fox, Michaela Waak, Peter B Sporns, Janette A Mailo, Lauren A Beslow, Max Wintermark, Melissa G Chung, Dana B Harrar, Arastoo Vossough and 20 more

Abstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Code ICH: Building Consensus in Pediatric Intracerebral Hemorrhage.Journal of the American Heart Association · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors.

Grégoire BoulouisDiagnostic and Interventional Neuroradiology CIC-IT 1415, CHRU de Tours, INSERM 1253 iBrain Tours Centre Val de Loire France.ORCID 0000-0001-8422-9205
Christine K FoxDepartments of Neurology and Pediatrics University of California San Francisco San Francisco CA USA.ORCID 0000-0001-6934-3624
Michaela WaakQueensland Children's Hospital Paediatric Intensive Care Unit South Brisbane Queensland Australia.ORCID 0000-0002-8317-3331
Peter B SpornsDepartment of Neuroradiology University Hospital Basel Basel Switzerland.ORCID 0000-0002-3028-0539
Janette A MailoDivision of Pediatric Neurology, Department of Pediatrics University of Alberta Edmonton Alberta Canada.
Lauren A BeslowDivision of Neurology, Children's Hospital of Philadelphia, Departments of Neurology and Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia PA USA.ORCID 0000-0003-0571-980X
Max WintermarkDepartment of Neuroradiology MD Anderson Houston TX USA.ORCID 0000-0002-6726-3951
Melissa G ChungDepartment of Pediatrics, Divisions of Pediatric Neurology and Critical Care Medicine Nationwide Children's Hospital Columbus OH USA.
Dana B HarrarDepartment of Neurology Children's National Hospital Washington DC USA.ORCID 0000-0001-6382-8479
Arastoo VossoughDepartment of Radiology Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0003-1346-427X
Moran Hausman-KedemPediatric Neurology Institute, Dana-Dwek Children's Hospital, Tel Aviv Medical Center Tel Aviv Israel.ORCID 0000-0001-5315-3738
Olivier NaggaraFrench National Reference Center for Pediatric Stroke Paris France.ORCID 0000-0002-9544-379X
Bin JiangDepartment of Radiology, Neuroradiology Section Stanford University Stanford CA USA.ORCID 0000-0002-8507-0459
Flavio RequejoDepartment of Neuroradiology JP Garrahan National Pediatric Hospital Buenos Aires Argentina.ORCID 0000-0001-5070-0329
Neeraj ChaudharyDepartment of Radiology University of Michigan Ann Arbor MI USA.ORCID 0000-0003-0630-2547
Sandro BenichiDepartment of Pediatric Neurosurgery, Assistance Publique-Hôpitaux de Paris Necker-Enfants Malades Hospital, Université Paris Cité Paris France.ORCID 0000-0003-1143-2987
Martin G RadvanyRadiology in the Department of Clinical Sciences Nova Southeastern University Dr. Kiran C Patel College of Allopathic Medicine Davie FL USA.ORCID 0000-0002-3627-8296
Mesha MartinezEdward Singleton Department of Radiology Texas Children's Hospital Austin TX USA.ORCID 0000-0003-3643-4401
Sudhakar VadiveluDepartment of Neurosurgery Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0003-1419-5673
Akash P KansagraDepartment of Neurointerventional Surgery California Center for Neurointerventional Surgery San Diego CA USA.ORCID 0000-0002-9201-4551
Beverly Aagaard-KienitzDepartment of Neurological Surgery University of Wisconsin School of Medicine and Public Health Madison WI USA.
Joan Martí-FàbregasStroke Unit Department of Neurology Hospital de la Santa Creu i Sant Pau Barcelona Barcelona Spain.
Mahesh ChikkannaiahDepartment of Neurology Dayton Children's Hospital Dayton OH USA.
Marco PasiStroke Unit, Neurology Department CIC-IT 1415, CHRU de Tours, INSERM 1253 iBrain Tours Centre Val de Loire France.ORCID 0000-0001-9976-2459
Jonathan A GrossbergDepartment of Neurosurgery Emory University Hospital Atlanta GA USA.ORCID 0000-0002-1152-8826
Mathilde ChevignardRehabilitation Department for Children with Acquired Neurological Injury Saint Maurice Hospitals, Saint Maurice. Sorbonne Université, INSERM, CNRS, Laboratoire d'Imagerie Biomédicale, LIB Paris France.
Christine MrakotskyDepartments of Neurology & Psychiatry Boston Children's Hospital, Harvard Medical School Boston MA USA.ORCID 0000-0002-9775-5906
Heather J FullertonDepartments of Neurology and Pediatrics University of California San Francisco San Francisco CA USA.ORCID 0000-0002-4828-1687
Nomazulu DlaminiDivision of Neurology The Hospital for Sick Children Toronto Ontario Canada.ORCID 0000-0001-5927-3132
Laura L LehmanDepartment of Neurology Boston Children's Hospital Boston MA USA.ORCID 0000-0002-6007-0356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric intracerebral hemorrhage (pICH) is a rare but serious neurologic emergency associated with significant morbidity. Although pICH accounts for nearly half of all pediatric strokes, it remains understudied, and dedicated evidence-based management guidelines are lacking. To address this gap, the International Pediatric Stroke Organization convened a multidisciplinary international working group in 2020 to develop a comprehensive, consensus-based framework for the acute evaluation and management of pICH in children aged 28 days to 18 years. The working group included child neurologists, neurointensivists, neurosurgeons, neuroradiologists, and neurointerventionalists. Subgroups conducted systematic literature reviews and formulated key clinical questions. A modified Delphi process was used to derive consensus statements across 6 domains: prehospital and emergency care, diagnostic imaging and workup, neurocritical care and medical management, neurosurgical and neurointerventional approaches, and identification of knowledge gaps. Through rounds of structured review and voting, 21 consensus statements were developed and approved. The process was endorsed by multiple professional societies. This represents the first international, multidisciplinary, multisociety consensus statement focused on the acute management of pICH in children. It provides structured, expert-driven guidance to inform clinical decision-making, reduce practice variability, and highlight areas for future research. These consensus statements aim to support clinicians worldwide in improving outcomes for children with pICH.

Indexed as

Cerebral HemorrhageStrokeAdolescentChildChild, PreschoolDelphi TechniqueHumansInfantInfant, Newbornnontraumatic cerebral hemorrhagepediatric hemorrhagic strokepediatric intracerebral hemorrhage

Identifiers

PMID41467366
PMCPMC12909056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.