Evidence map›Paper›PMID 41467320›Full record

SynthesisThe Laryngoscope2026

Outcomes and Innervation of Gracilis for Pediatric Facial Paralysis: A Systematic Review.

Kaiwen Chen, Shaun A Nguyen, Warren B Chun, Charles M Henry, Matthew H Cheung, Cory Hyun-Su Kim, Michelle S Hwang

Abstract readSystematic Review
In one paragraph

Synthesis in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaiwen ChenDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Shaun A NguyenDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0003-0664-4571
Warren B ChunDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Charles M HenryDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Matthew H CheungDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Cory Hyun-Su KimDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0003-1604-4975
Michelle S HwangDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis systematic review aims to describe and compare outcomes of innervation techniques for gracilis free muscle transfers for facial reanimation in the pediatric population. DATA SOURCES: CINAHL, PubMed, and SCOPUS were systematically queried from inception to November 18, 2025. REVIEW

methodsEligible studies included pediatric patients (≤ 18 years old) who underwent free gracilis muscle transfer for facial reanimation. Outcomes extracted included commissure excursion, facial asymmetry, validated instruments, patient satisfaction, and complications. Study quality was assessed using the Joanna Briggs Institute appraisal tool.

resultsA total of 15 retrospective studies were included for review, covering cross-facial nerve graft, masseteric innervation, and dual-innervation. The mean age at time of surgery was 9.0 ± 0.8 years with a mean follow-up time of 3.0 ± 0.5 years. Muscle innervation was achieved primarily with CFNG (52.1%), followed by masseteric (33.2%). Masseteric innervation generally produced the largest amount of commissure excursion (range: 6.1-8.6 mm), while CFNG also yielded moderate improvements (range: 4.6-6.9 mm). Overall satisfaction was high for all innervation techniques, ranging from 83% to 100%. Complications were infrequent and minor.

conclusionGracilis free muscle transfer is safe and effective for pediatric facial reanimation. Masseteric innervation provides strong, volitional smiles, while CFNG provides spontaneous smiles, with dual-innervation offering a balance of the two.

Indexed as

Facial ParalysisFree Tissue FlapsGracilis MuscleNerve TransferAdolescentChildFacial NerveHumansRetrospective StudiesTreatment Outcomecross‐facial nerve graftgracilis free muscle transfermasseteric nerve innervationpediatric facial paralysis

Identifiers

PMID41467320
PMCPMC13158824

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.